Pericytes or Mesenchymal Stem Cells: Is That the Question?
Cano, E.; Gebala, Véronique.; Gerhardt, H.
Cell Stem Cell 20(3): 296-297
2017
ISSN/ISBN: 1934-5909
PMID: 28257708
DOI: 10.1016/j.stem.2017.02.005
Accession: 060080715
For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimarães-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.