+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Pseudoexfoliation: An Ocular Finding with Possible Systemic Implications



Pseudoexfoliation: An Ocular Finding with Possible Systemic Implications



Israel Medical Association Journal 19(1): 49-54



Pseudoexfoliation syndrome (PES) is a common age-related disorder affecting 60-70 million people worldwide. Patients with PES have abnormal production and deposition of fibrillar material in the anterior chamber of the eye. These exfoliated fibrils, easily detected by ocular slit-lamp examination, have also been found to exist systematically in the skin, heart, lungs, liver and kidneys. Recently, myriad studies have associated PES with systemic conditions such as increased vascular risk, risk of dementia and inflammatory state. We review here the most current literature on the systemic implications of PES. Our aim is to encourage further studies on this important clinical entity.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 060149708

Download citation: RISBibTeXText

PMID: 28457115


Related references

Ocular and systemic pseudoexfoliation syndrome. American Journal of Ophthalmology 141(5): 921-937, 2006

Pseudoexfoliation syndrome. Ocular manifestation of a systemic disorder?. Archives of Ophthalmology 110(12): 1752-1756, 1992

Pseudoexfoliation syndrome, a systemic disorder with ocular manifestations. Human Genomics 6: 22, 2012

Prevalence of pseudoexfoliation syndrome and its association with ocular and systemic diseases in Eskisehir, Turkey. International Journal of Ophthalmology 10(1): 128-134, 2017

Pseudoexfoliation of the lens capsule part 3 ocular tension in eyes with pseudoexfoliation. Acta Ophthalmologica: 446-454, 1970

Pseudoexfoliation of the lens capsule. 3. Ocular tension in eyes with pseudoexfoliation. Acta Ophthalmologica 48(3): 446-454, 1970

Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Ophthalmology 108(6): 1043-1049, 2001

Systemic high-sensitivity C-reactive protein level in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Journal of Glaucoma 19(6): 373-376, 2010

Nasal and conjunctival contributions to the systemic absorption of topical timolol in the pigmented rabbit: implications in the design of strategies to maximize the ratio of ocular to systemic absorption. Journal of Ocular Pharmacology 3(2): 159-169, 1987

Pfeiffer syndrome: systemic and ocular implications. Optometry 76(7): 352-362, 2005

Ocular pseudoexfoliation syndrome. Medicinski Pregled 63(9-10): 681-688, 2011

The finding of anticardiolipin autoantibodies in patients with pseudoexfoliation syndrome requires further evaluation. Journal of Glaucoma 21(3): 206; Author Reply 206-7, 2012

Plateletcrit in Ocular Pseudoexfoliation Syndrome. Eye and Contact Lens 42(5): 328-332, 2016

Ocular pseudoexfoliation associated with hearing loss. Saudi Medical Journal 25(9): 1254-1257, 2004

Therapeutic implications of ocular involvement in systemic degenerative diseases. La Clinica Terapeutica 108(5): 427-431, 1984