Reference standards for lean mass measures using GE dual energy x-ray absorptiometry in Caucasian adults
Imboden, M.T.; Swartz, A.M.; Finch, H.W.; Harber, M.P.; Kaminsky, L.A.
Plos one 12(4): E0176161
ISSN/ISBN: 1932-6203 PMID: 28426779 DOI: 10.1371/journal.pone.0176161
To develop reference values by age and sex for LM measures using GE-Healthcare DXA systems. A de-identified sample was obtained from Ball State University's Clinical Exercise Physiology Laboratory and University of Wisconsin-Milwaukee's Physical Activity & Health Research Laboratory. DXA scans of 2,076 women and 1,251 men were completed using a GE Lunar Prodigy or iDXA. Percentiles (%ile) were calculated for all variables of interest (LM, LMI, %LM, and ALMI) and a factorial ANOVA was used to assess differences for each variable between 10-year age groups and sex, as well as the interaction between age and sex. Men had higher mean total LM, %LM, LMI, and ALMI than women (p<0.01), across all age groups. All LM variables decreased significantly over the 5 decades in men, however in women only total LM, %LM, and ALMI decreased from the youngest to oldest age groups (p<0.01). These reference values provide for a more accurate interpretation of GE-Healthcare DXA-derived LM measurements offering clinicians and researchers with an initial resource to aid in the early detection and assessment of LM deficits.