+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Risk Factors for Intrapartum Fever in Term Gestations and Associated Maternal and Neonatal Sequelae



Risk Factors for Intrapartum Fever in Term Gestations and Associated Maternal and Neonatal Sequelae



Gynecologic and Obstetric Investigation 82(5): 508-516



To determine factors associated with intrapartum fever and to examine associated maternal and neonatal outcomes. Retrospective study of patients between 360/7 and 420/7 gestational weeks who entered spontaneous or induced active labor and developed temperature ≥38°C; a similar group that did not develop fever were controls. Univariate and multivariate analyses were performed with p < 0.05 as significant. Fifty-four febrile patients and 306 nonfebrile controls met inclusion criteria. Nulligravidity (45.8 vs. 77.8%, p < 0.001), length of first stage ≥720 min (OR 3.59, 95% CI 1.97-6.55, p < 0.001), length of second stage ≥120 min (OR 4.76, 95% CI 2.29-9.89, p < 0.001), membrane rupture ≥240 min (46.4 vs. 79.6%, p < 0.001), increasing number of vaginal exams (4 vs. 6, p < 0.001), oxytocin (44.8 vs. 63.0%, p = 0.014), and meperidine (14.7 vs. 35.2%, p < 0.001) were all associated with intrapartum fever. Associated morbidity included cesarean delivery (22.5 vs. 44.4%, p = 0.001), Apgar score <7 at 5 min (0.7 vs. 5.6%, p = 0.011), and neonatal intensive care unit admission (9.5 vs. 51.9%, p < 0.001). We have identified several noninfectious factors that are associated with intrapartum fever. Modification of risk factors may improve both maternal and neonatal outcomes.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 060210709

Download citation: RISBibTeXText

PMID: 28103590

DOI: 10.1159/000453611


Related references

Risk factors for maternal intrapartum fever and short-term neonatal outcome. Fetal and Pediatric Pathology 25(3): 169-177, 2006

The relationship between intrapartum maternal fever and neonatal acidosis as risk factors for neonatal encephalopathy. American Journal of Obstetrics and Gynecology 198(1): 49.E1-6, 2008

The Relationship Between Intrapartum Maternal Fever and Neonatal Acidosis as Risk Factors for Neonatal Encephalopathy. Obstetric Anesthesia Digest 28(3): 167-168, 2008

Interaction between intrapartum maternal fever and fetal acidosis increases risk for neonatal encephalopathy. American Journal of Obstetrics and Gynecology 199(2): E9; Author Reply E9, 2008

Antepartum and intrapartum risk factors for neonatal encephalopathy at term. American Journal of Perinatology 27(8): 649-654, 2010

Perinatal Risk Factors for Neonatal Early-onset Group B Streptococcal Sepsis after Initiation of Risk-based Maternal Intrapartum Antibiotic Prophylaxis-A Case Control Study. Journal of Tropical Pediatrics 64(4): 312-316, 2018

The efffect of histologic chorioaminionitis on risk factors for intrapartum fever in the term parturient. 2007

Intrapartum maternal fever and neonatal outcome. Pediatrics 105(1 Pt 1): 8-13, 2000

Intrapartum Maternal Fever and Neonatal Outcome. Pediatrics 105(1): 8-13, 2000

Neonatal hematogenous osteomyelitis: risk factors for long-term sequelae. Journal of Pediatric Orthopedics 5(5): 564-568, 1985

Neonatal, maternal, and intrapartum factors and their relationship to cord-and maternal-plasma trace-element concentration. Biological Trace Element Research 9(4): 209-219, 1986

Maternal and neonatal outcome in deliveries complicated by intrapartum fever - does time to delivery matter?. American Journal of Obstetrics and Gynecology 216(1): S401-S402, 2017

Management of term newborns following maternal intrapartum fever. Journal of Maternal-Fetal and Neonatal Medicine 26(2): 207-210, 2013

Intrapartum maternal fever Is this a risk factor?. Pediatric Research 49(4 Part 2): 402A, 2001

Approach to term neonates born after maternal intrapartum fever and unknown maternal group B Streptococcus status: value of serum C-reactive protein and 16S rRNA gene PCR amplification. Pediatric Infectious Disease Journal 26(11): 1064-1066, 2007