+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Role of the microbiota in skin immunity and atopic dermatitis



Role of the microbiota in skin immunity and atopic dermatitis



Allergology International 66(4): 539-544



Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects 15-20% of children and 2-5% of adults in industrialized countries. The pathogen Staphylococcus aureus selectively colonizes the lesional skin of AD patients while this bacterium is absent in the skin of the majority of healthy individuals. However, the role of S. aureus in the pathogenesis of AD remains poorly understood. In addition to S. aureus, recent studies show a contribution of the skin microbiota to the regulation of immune responses in the skin as well as to the development of inflammatory skin disease. This review summarizes current knowledge about the role of the microbiota in skin immune responses and the role of S. aureus virulent factors in the pathogenesis of AD.

(PDF emailed within 0-6 h: $19.90)

Accession: 060218002

Download citation: RISBibTeXText

PMID: 28882556

DOI: 10.1016/j.alit.2017.08.004


Related references

Interaction of orally administered Lactobacillus rhamnosus GG with skin and gut microbiota and humoral immunity in infants with atopic dermatitis. Clinical and Experimental Allergy 41(3): 370-377, 2011

Characterization of skin microbiota in patients with atopic dermatitis. Journal of Medical Microbiology 56(12): 1675-1683, 2007

Skin microbiota and atopic dermatitis: toward new therapeutic options?. Annales de Dermatologie et de Venereologie 142 Suppl 1: S18-S22, 2015

Occurrence of patchy parakeratosis in normal-appearing skin in patients with active atopic dermatitis and in patients with healed atopic dermatitis: A cause of impaired barrier function of the atopic skin. Journal of Dermatological Science 30(1): 37-42, 2002

Skin microbiota of first cousins affected by psoriasis and atopic dermatitis. Clinical and Molecular Allergy 14: 2, 2016

Transplantation of human skin microbiota in models of atopic dermatitis. Jci Insight 1(10), 2016

Inverse Association Between the Skin and Oral Microbiota in Atopic Dermatitis. Journal of Investigative Dermatology 2019, 2019

Dietetic effects of oral intervention with mare's milk on the Severity Scoring of Atopic Dermatitis, on faecal microbiota and on immunological parameters in patients with atopic dermatitis. International Journal of Food Sciences and Nutrition 60 Suppl 7: 41-52, 2010

Microecological and electron microscopic study of skin microbiota in patients with atopic dermatitis. Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii 2010(1): 67-72, 2010

Characterization of the skin fungal microbiota in patients with atopic dermatitis and healthy subjects. 2011

The effect of UVB radiation on skin microbiota in patients with atopic dermatitis and healthy controls. International Journal of Circumpolar Health 67(2-3): 254-260, 2008

Characterization of the skin fungal microbiota in patients with atopic dermatitis and in healthy subjects. Microbiology and Immunology 55(9): 625-632, 2012

Molecular analysis of the cutaneous Malassezia microbiota from the skin of patients with atopic dermatitis of different severities. Mycoses 54(4): E24-E28, 2011

Clinical efficacy of emollients in atopic dermatitis patients - relationship with the skin microbiota modification. Clinical, Cosmetic and Investigational Dermatology 10: 25-33, 2017

Assessment of a correlation between Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) and selected biophysical skin measures (skin hydration, pH, and erythema intensity) in dogs with naturally occurring atopic dermatitis. Canadian Journal of Veterinary Research 79(2): 136-140, 2016