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Solid-phase synthesis of peptide selenoesters via a side-chain anchoring strategy

Hanna, C.C.; Kulkarni, S.S.; Watson, E.E.; Premdjee, B.; Payne, R.J.

Chemical Communications 53(39): 5424-5427

2017

ISSN/ISBN: 1364-548X
PMID: 28462972
DOI: 10.1039/c7cc00823f
Accession: 060262870
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Peptide selenoesters have recently emerged as key building blocks for the ligation-based assembly of large polypeptides and proteins. Herein, we report an efficient solid-phase method for the high yielding and epimerisation-free synthesis of peptide selenoesters using a side-chain immobilisation strategy.

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Related References

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