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Synthesis of 1-Azaanthraquinone: Sequential C-N Bond Formation/Lewis Acid Catalyzed Intramolecular Cyclization Strategy



Synthesis of 1-Azaanthraquinone: Sequential C-N Bond Formation/Lewis Acid Catalyzed Intramolecular Cyclization Strategy



Journal of Organic Chemistry 82(15): 8309-8316



A synthetic strategy has been developed for the synthesis of 1-azaanthraquinones. This synthetic protocol consists of sequential Pd-catalyzed carbon-nitrogen bond formation followed by Lewis acid catalyzed intramolecular cyclization. The Pd-catalyzed aminated intermediate was isolated and characterized. This sequential reactions strategy provides a wide range of 1-azaanthraquinones with good yields.

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Accession: 060308253

Download citation: RISBibTeXText

PMID: 28677967

DOI: 10.1021/acs.joc.7b01427


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