The Association Between Handgrip Strength and Diabetes on Activities of Daily Living Disability in Older Mexican Americans

McGrath, R.P.; Vincent, B.M.; Snih, S.Al.; Markides, K.S.; Dieter, B.P.; Bailey, R.R.; Peterson, M.D.

Journal of Aging and Health 30(8): 1305-1318


ISSN/ISBN: 0898-2643
PMID: 28627325
DOI: 10.1177/0898264317715544
Accession: 060327299

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The aim of this study is to determine the independent and joint effects of muscle weakness and diabetes on incident activities of daily living (ADL) disability in older Mexican Americans. A subsample of 2,270 Mexican Americans aged at least 65 years at baseline were followed for 19 years. Handgrip strength was normalized to body weight (normalized grip strength [NGS]). Weakness was defined as NGS ≤0.46 in males and ≤0.30 in females. Diabetes and ADL disability were self-reported. Compared with participants that were not weak and did not have diabetes, those that had diabetes only, were weak only, and were both weak and had diabetes experienced a 1.94 (95% confidence interval [CI] = [1.89, 1.98]), 1.17 (CI = [1.16, 1.19]), and 2.12 (CI = [2.08, 2.16]) higher rate for ADL disability, respectively. Muscle weakness and diabetes were independently and jointly associated with higher rates for ADL disability in older Mexican Americans.