+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The prognostic value of nodal skip metastasis in resectable thoracic esophageal squamous cell carcinoma



The prognostic value of nodal skip metastasis in resectable thoracic esophageal squamous cell carcinoma



Oncotargets and Therapy 10: 2729-2736



This study aimed to investigate the incidence of nodal skip metastasis (NSM) to identify the risk factors that influence NSM and to assess the prognostic value of NSM in patients with thoracic esophageal squamous cell carcinoma (ESCC). Between January 2009 and December 2013, 285 patients with ESCC with positive lymph nodes who underwent complete resection were enrolled. For the entire group, NSM occurred in 32.3% (92/285) of patients. The median survival time and 5-year survival rate in the NSM group were 28 months and 12.0%, respectively, compared with 36.3 months and 25.0%, respectively, in the non-NSM group (P=0.008). Both N stage (P=0.001) and T stage (P=0.014) were associated with the incidence of NSM. NSM (P=0.008), T stage (P=0.000), and N stage (P=0.000) were independent prognostic factors for survival. In the NSM group, T stage (P=0.014) and N stage (P=0.000) were independent prognostic factors for survival. It was concluded that NSM is common in ESCC and is associated with poor survival.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 060376380

Download citation: RISBibTeXText

PMID: 28579811

DOI: 10.2147/ott.s132062


Related references

Prognostic evaluation of nodal skip metastasis for thoracic Esophageal Squamous Cell Carcinoma. Annals of Thoracic Surgery 2019, 2019

Nodal skip metastasis is associated with a relatively poor prognosis in thoracic esophageal squamous cell carcinoma. European Journal of Surgical Oncology 42(8): 1202-1205, 2017

Nodal skip metastasis in thoracic esophageal squamous cell carcinoma: a cohort study. Bmc Surgery 17(1): 49, 2017

Nodal skip metastasis is not a predictor of survival in thoracic esophageal squamous cell carcinoma. Annals of Surgical Oncology 20(9): 3052-3058, 2014

Elucidation of the Anatomical Mechanism of Nodal Skip Metastasis in Superficial Thoracic Esophageal Squamous Cell Carcinoma. Annals of Surgical Oncology 25(5): 1221-1228, 2018

Nodal Skip Metastasis in Esophageal Squamous Cell Carcinoma Patients Undergoing Three-Field Lymphadenectomy. Annals of Thoracic Surgery 104(4): 1187-1193, 2017

Efficacy and prognostic analysis of chemoradiotherapy in patients with thoracic esophageal squamous carcinoma with cervical lymph nodal metastasis alone. Radiation Oncology 9: 256, 2015

Prognostic value of thoracic recurrent nerve nodal involvement in esophageal squamous cell carcinoma. Journal of the American College of Surgeons 185(3): 244-249, 1997

Pretreatment NRS-2002 scores combined with hematologic inflammation markers are independent prognostic factors in patients with resectable thoracic esophageal squamous cell carcinoma. Cancer Management and Research 10: 2409-2418, 2018

Isolated skip nodal metastasis is rare in T1 and T2 oral tongue squamous cell carcinoma. Otolaryngology--Head and Neck Surgery 147(2): 275-277, 2012

Prognostic Significance of (18)F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET)-Positive Lymph Nodes Following Neoadjuvant Chemotherapy and Surgery for Resectable Thoracic Esophageal Squamous Cell Carcinoma. Annals of Surgical Oncology 22(8): 2599-2607, 2016

Prognostic analysis of cervical lymph node metastasis in patients with thoracic esophageal squamous cell carcinoma. Zhonghua Zhong Liu Za Zhi 36(8): 612-616, 2015

Unilateral cervical nodal metastasis is an independent prognostic factor for esophageal squamous cell carcinoma patients undergoing chemoradiotherapy: a retrospective study. Plos One 9(6): E101332, 2015

The pretreatment Controlling Nutritional Status (CONUT) score is an independent prognostic factor in patients with resectable thoracic esophageal squamous cell carcinoma: results from a retrospective study. Bmc Cancer 16: 722, 2017

The patterns and prognostic factors of abdominal lymph node metastasis in patients with the middle thoracic esophageal squamous cell carcinoma. Zhonghua Wai Ke Za Zhi 46(23): 1800-1803, 2009