+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effects of Timely Control Intervention on the Spread of Middle East Respiratory Syndrome Coronavirus Infection



Effects of Timely Control Intervention on the Spread of Middle East Respiratory Syndrome Coronavirus Infection



Osong Public Health and Research Perspectives 8(6): 373-376



The 2015 Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreak in Korea caused major economic and social problems. The control intervention was conducted during the MERS-CoV outbreak in Korea immediately after the confirmation of the index case. This study investigates whether the early risk communication with the general public and mass media is an effective preventive strategy. The SEIR (Susceptible, Exposed, Infectious, Recovered) model with estimated parameters for the time series data of the daily MERS-CoV incidence in Korea was considered from May to December 2015. For 10,000 stochastic simulations, the SEIR model was computed using the Gillespie algorithm. Depending on the time of control intervention on the 20th, 40th, and 60th days after the identification of the index case, the box plots of MERS-CoV incidences in Korea were computed, and the results were analyzed via ANOVA. The box plots showed that there was a significant difference between the non-intervention and intervention groups (the 20th day, 40th day, and 60th day groups) and seemed to show no significant difference based on the time of intervention. However, the ANOVA revealed that early intervention was a good strategy to control the disease. Appropriate risk communication can secure the confidence of the general public in the public health authorities.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 060641815

Download citation: RISBibTeXText

PMID: 29354394


Related references

What needs to be done to control the spread of Middle East respiratory syndrome coronavirus?. Future Virology 10(5): 497-505, 2015

Assessing the Detection of Middle East Respiratory Syndrome Coronavirus IgG in Suspected and Proven Cases of Middle East Respiratory Syndrome Coronavirus Infection. Viral Immunology 30(9): 649-653, 2017

Assessment of the Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic in the Middle East and risk of international spread using a novel maximum likelihood analysis approach. Euro Surveillance 19(23):, 2014

Middle East respiratory syndrome coronavirus infection control: the missing piece?. American Journal of Infection Control 42(12): 1258-1260, 2014

Infection prevention and control guidelines for patients with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. Saudi Medical Journal 35(8): 897-913, 2014

Middle East respiratory syndrome coronavirus (MERS-CoV) viral shedding in the respiratory tract: an observational analysis with infection control implications. International Journal of Infectious Diseases 29: 307-308, 2014

Proficiency testing for the detection of Middle East respiratory syndrome coronavirus demonstrates global capacity to detect Middle East respiratory syndrome coronavirus. Journal of Medical Virology 90(12): 1827-1833, 2018

Asymptomatic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: Extent and implications for infection control: A systematic review. Travel Medicine and Infectious Disease 27: 27-32, 2018

Middle East Respiratory Syndrome Coronavirus and Pulmonary Tuberculosis Coinfection: Implications for Infection Control. Intervirology 60(1-2): 53-55, 2017

Infection control influence of Middle East respiratory syndrome coronavirus: A hospital-based analysis. American Journal of Infection Control 47(4): 431-434, 2019

Middle East respiratory syndrome coronavirus intermittent positive cases: Implications for infection control. American Journal of Infection Control 47(3): 290-293, 2019

Middle East Respiratory Syndrome Coronavirus Transmission in Dialysis Unit and Infection Control Interventions in Korea. Infection Control and Hospital Epidemiology 37(12): 1514-1516, 2016

Middle East respiratory syndrome coronavirus transmission among health care workers: Implication for infection control. American Journal of Infection Control 46(2): 165-168, 2018

Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus. Mbio 5(1):, 2014

Modeling the spread of Middle East respiratory syndrome coronavirus in Saudi Arabia. Statistical Methods in Medical Research 27(7): 1968-1978, 2018