Studies of polyarthritis and other lesions induced in rats by injection of mycobacterial adjuvant. I. General clinical and pathologic characteristics and some modifying factors
Carl, M. Pearson; Fae, D. Wood
Arthritis and Rheumatism 2(5): 440-459
ISSN/ISBN: 2326-5191 DOI: 10.1002/1529-0131(195910)2:5<440::aid-art1780020510>3.0.co;2-n
A reproducible polyarthritis was induced in rats by administering an emulsion of mineral oil and certain mycobacteria. Associated nonarticular lesions were observed. Pathogenesis of this experimental disease apparently involves hypersensitivity.