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Studies of polyarthritis and other lesions induced in rats by injection of mycobacterial adjuvant. I. General clinical and pathologic characteristics and some modifying factors

Carl, M. Pearson; Fae, D. Wood

Arthritis and Rheumatism 2(5): 440-459

1959

ISSN/ISBN: 2326-5191
DOI: 10.1002/1529-0131(195910)2:5<440::aid-art1780020510>3.0.co;2-n
Accession: 060997119
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A reproducible polyarthritis was induced in rats by administering an emulsion of mineral oil and certain mycobacteria. Associated nonarticular lesions were observed. Pathogenesis of this experimental disease apparently involves hypersensitivity.

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Related References

Pearson, C.M.; Wood, F.D. 1959: Studies of polyarthritis and other lesions induced in rats by injection of mycobacterial adjuvant. 1. General clinical and pathologic characteristics and some modifying factors Arthritis and Rheumatism 2(5): 440-459
Mellinkoff, S.M.; Pearson, C.M.; Wood, F.D.; Eshelman, O.; Dixon, W. 1962: Studies of Polyarthritis Induced in Rats by Injection of Mycobacterial Adjuvant The American Journal of Clinical Nutrition 10(5): 398-402
Pearson, C.M.; Wood, F.D. 1963: Studies of arthritis and other lesions induced in rats by the injection of mycobacterial adjuvant. VII. Pathologic details of the arthritis and spondylitis American Journal of Pathology 42: 73-95
Mellinkoff, S.M.; Pearson, C.M.; Wood, F.D.; Eshelmano; Dixon, W. 1962: Studies of polyarthritis induced in rats by injection of mycobacterial adjuvant. VI. Effects of dietary alterations American Journal of Clinical Nutrition 10: 398-402
Waksman, B.H.; Bullington, S.J. 1960: Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. III. Lesions of the eye Archives of Ophthalmology 64: 751-762
John, T.S.; Byron, H.W.; Carl, M.P.; Sarabelle Madoff 1961: Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant IV Examination of tissues and fluids for infectious agents Arthritis and Rheumatism 4(2): 169-175
Waksman, B.H.; Pearson, C.M.; Sharp, J.T. 1960: Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. II. Evidence that the disease is a disseminated immunologic response to exogenous antigen Journal of Immunology 85: 403-417
Pearson, C.M.; Waksman, B.H.; Sharp, J.T. 1961: Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. V. Changes affecting the skin and mucous membranes. Comparison of the experimental process with human disease Journal of Experimental Medicine 113: 485-510
Ward, J.R.; Jones, R.S. 1962: Studies on adjuvant-induced polyarthritis in rats. I. Adjuvant composition, route of injection, and removal of depot site Arthritis and Rheumatism 5: 557-564
Jones, R.S.; Ward, J.R. 1963: Studies on adjuvant-induced polyarthritis in rats. II. Histogenesis of joint and visceral lesions Arthritis and Rheumatism 6: 23-35
Brajczewska-Fischer, W.; Szpilman, H.; Ryzèwska, A. 1979: Modifying action of levamisole on the course of adjuvant-induced polyarthritis in rats Archivum Immunologiae et Therapiae Experimentalis 27(1-2): 241-246
Jadot, G.; Michelson, A.M.; Puget, K. 1986: Anti-inflammatory activity of superoxide dismutases: studies on adjuvant induced polyarthritis in rats Free Radical Research Communications 2(1-2): 27-42
Coimbra, Joao Carlos; Pinto, Iraja Damiani; Wurdig, Norma Luiza; Do Carmo, Dermeval Aparecido 1964: Studies on adjuvant-induced polyarthritis in rats. III. The effect of immunosuppressive agents on arthritis and tuberculin hypersensitivity Arthritis and Rheumatism 7(6): 654-661
Ward, J.R.; Cloud, R.S.; Krawitt, E.L.; Jones, R.S. 1964: Studies on adjuvant-induced polyarthritis in rats. HI. The effect of immunosuppressive agents on arthritis and tuberculin hyper-sensitivlty Arthritis and Rheumatism 7(6): 654-661
Geiler, G.; Keitel, W.; Franke, A. 1975: Comparative morphological studies on adjuvant arthritis induced in the extremities of rats, mice, and golden hamsters by intracutaneous injection of Freund's complete adjuvant Experimentelle Pathologie 10(1-2): 72-82
Ryzewska, A. 1969: Influence of the composition of Freund's adjuvant, strain and sex of animals on the course of adjuvant--induced polyarthritis in rats Reumatologia 7(3): 195-206
Strafuss, A.C.; Sautter, J.H. 1967: Pathologic characteristics of renal lesions induced by S- -L-cvsteine in calves and rats American Journal of Veterinary Research 28: 1805-1815
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Mikulski, A. 1967: Studies on the retention of tritium derived from tritium water (HTO) in the tissues and body fluids of rats with adjuvant-induced polyarthritis Reumatologia 5(4): 335-347
Ward, J.R.; Cloud, R.S.; Krawitt, E.L.; Jones, R.S. 1964: Studies on Adjuvant-Induced Polyarthritis in Rats. 3. the Effect of "immunosuppressive Agents" on Arthritis and Tuberculin Hypersensitivity Arthritis and Rheumatism 7: 654-661