Effect of Antibiotics on Mice Treated With Cyclophosphamide 2
Bruckner, H W.
Jnci Journal of the National Cancer Institute 57(6): 1249-1252
The toxicity and therapeutic index of cyclophosphamide (CP) in NIH Wwiss and (C57BL X DBA)F mice were affected by the addition of different antibiotics to the drinking water. Penicillin G or Vancomycin increased the rat and number of deaths that followed parenteral treatment with CP; however, penicillin or Vancomycin alone produced no deaths.