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A relationship between plasmid structure, structural lability, and sensitivity to site-specific endonucleases inNeisseria gonorrhoeae

John, K. Davies; Staffan Normark

Molecular Genetics and Genomics 177(2): 251-260

1980

ISSN/ISBN: 1617-4615
DOI: 10.1007/bf00267436
Accession: 061566972
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Nearly all gonococcal strains carry a small "phenotypically cryptic" plasmid of approximately 4,200 basepairs. A detailed physical map of this plasmid has been constructed, revealing the presence of numerous putative inverted repeats. These studies also revealed the presence on the plasmid of recognition sequences for several site-specific endonucleases (particularly HpaII, MspI and AluI) that are particularly resistant to cleavage, and confirmed previous reports of structural lability.

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Related References

Davies, J.K.; Normark, S. 1980: A relationship between plasmid structure, structural lability, and sensitivity to site-specific endonucleases in Neisseria gonorrhoeae Molecular and General Genetics: Mgg 177(2): 251-260
van Klingeren, B.; Ansink, M.-Schipper, C; Dessens-Kroon, M; Woudstra, R.K.; Huikeshoven, M.H. 1985: Relationship between auxotype, plasmid pattern and sensitivity to antibiotics in penicillinase-producing Neisseria gonorrhoeae Antonie van Leeuwenhoek 51(4): 418-419
Hagblom, P.; Korch, C.; Jonsson, A.B.; Normark, S. 1986: Intragenic variation by site-specific recombination in the cryptic plasmid of Neisseria gonorrhoeae Journal of Bacteriology 167(1): 231-237
Mayer, L.W.; Robbins, K.E. 1983: Evolutionary analysis of the 7.1-kb beta-lactamase-specifying R-plasmid of Neisseria gonorrhoeae by restriction endonucleases Journal of Bacteriology 154(3): 1498-1501
Minocherhomji, S.; Hickson, I.D. 2014: Structure-specific endonucleases: guardians of fragile site stability Trends in Cell Biology 24(5): 321-327
Collins, J.; Mayer, H. 1980: Restriction endonucleases or the site-specific DNA endonucleases Arzneimittel-Forschung 30(3a): 541-547
Johnson, S.R.; Morse, S.A. 1991: The relationship between the 39 kb tetracycline-resistance plasmid and the 36 kb conjugative plasmid of Neisseria gonorrhoeae Journal of Antimicrobial ChemoTherapy 27(6): 864-867
Thompson, R.; Hughes, S.G.; Broda, P. 1974: Plasmid identification using specific endonucleases Molecular and General Genetics: Mgg 133(2): 141-149
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Causey, S.C.; Brown, L.R. 1978: Transconjugant analysis: limitations on the use of sequence-specific endonucleases for plasmid identification Journal of Bacteriology 135(3): 1070-1079
Sokolov, N.N.; Manialene, Z.P.; Butkus, V.V.; Fitsner, A.B.; Khoroshutina, E.B.; Kalugin, A.A.; Ianulaĭtis, A.A. 1990: Site-specific endonucleases LplI and AagI Bioorganicheskaia Khimiia 16(8): 1040-1044
Aggarwal, A.K.; Wah, D.A. 1998: Novel site-specific DNA endonucleases Current Opinion in Structural Biology 8(1): 19-25
Friedhoff, P.; Franke, I.; Meiss, G.; Wende, W.; Krause, K.L.; Pingoud, A. 1999: A similar active site for non-specific and specific endonucleases Nature Structural Biology 6(2): 112-113
Omer, C.A.; Cohen, S.N. 1986: Structural analysis of plasmid and chromosomal loci involved in site-specific excision and integration of the SLP1 element of Streptomyces coelicolor Journal of Bacteriology 166(3): 999-1006
Friedhoff, P.; Pingoud, A. 2007: Engineering site-specific endonucleases Methods in Molecular Biology 352: 111-123