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Chapter 61,944

Proline isomerization and the slow folding reactions of the α subunit of tryptophan synthase from Escherichia coli

Ziegelhoeffer A.; De Jong J.W.; Ferrari R.; Turi Nagy L.

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology 913(2): 179-184

1987

DOI: 10.1016/0167-4838(87)90328-1
Accession: 061943242
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Previous studies on the refolding of the alpha subunit of tryptophan synthase from Escherichia coli assigned two slow refolding phases to rate-limiting isomerizations of two 'essential' proline residues, one in each of the two domains of the protein (Matthews, C.R., Crisanti, M.M., Manz, J.T. and Gepner, G.L. (1983) Biochemistry 22, 1445-1452).

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Related References

Hurle, M.R.; Matthews, C.R. 1987: Proline isomerization and the slow folding reactions of the alpha subunit of tryptophan synthase from Escherichia coli Biochimica et Biophysica Acta 913(2): 179-184
Stackhouse, T.M.; Onuffer, J.J.; Matthews, C.R.; Ahmed, S.A.; Miles, E.W. 1988: Folding of hmologous proteins: conservation of the folding mechanism of the α subunit of tryptophan synthase from Escherichia coli, Salmonella typhimurium, and five interspecies hybrids Biochemistry (Easton) 27(2): 824-832
Stackhouse, T.M.; Onuffer, J.J.; Matthews, C.Robert 1988: Folding of homologous proteins: conservation of the folding mechanism of the a subunit of tryptophan synthase from Escherichia coli, Salmonella typhimurium, and five interspecies hybrids Biochemistry (American Chemical Society) 27: 4-32
Stackhouse, T.M.; Onuffer, J.J.; Matthews, C.R.; Ahmed, S.A.; Miles, E.W. 1988: Folding of homologous proteins: conservation of the folding mechanism of the alpha subunit of tryptophan synthase from Escherichia coli, Salmonella typhimurium, and five interspecies hybrids Biochemistry 27(2): 824-832
Chrunyk, B.A.; Matthews, C.R. 1990: Role of diffusion in the folding of the α subunit of tryptophan synthase from Escherichia coli Biochemistry (Easton) 29(8): 2149-2154
Chrunyk, B.A.; Matthews, C.Robert 1990: Role of diffusion in the folding of the a subunit of tryptophan synthase from Escherichia coli Biochemistry (American Chemical Society) 29: 49-54
Chrunyk, B.A.; Matthews, C.R. 1990: The role of position 49 in the folding of the alpha subunit of tryptophan synthase from escherichia coli Biophysical Journal 57(2 Part 2): 436A
Chrunyk, B.A.; Matthews, C.R. 1990: Role of diffusion in the folding of the alpha subunit of tryptophan synthase from Escherichia coli Biochemistry 29(8): 2149-2154
Chrunyk, B.A.; Tweedy, N.B.; Hurle, M.R.; Matthews, C.R. 1989: The effects of multiple replacements on the folding on the alpha subunit of tryptophan synthase from escherichia coli Journal of Cellular Biochemistry Suppl (13 Part A): 67
Nishio, K.; Morimoto, Y.; Ishizuka, M. 2005: Conformational Changes in the a-Subunit Coupled to Binding of the b2-Subunit of Tryptophan Synthase from Escherichia coli: Crystal Structure of the Tryptophan Synthase a-Subunit Alone Biochemistry (American Chemical Society) 44(4): 84-92
Gualfetti, P.J.; Bilsel, O.; Matthews, C.R. 1999: The progressive development of structure and stability during the equilibrium folding of the alpha subunit of tryptophan synthase from Escherichia coli Protein Science: a Publication of the Protein Society 8(8): 1623-1635
Blond, S.; Goldberg, M.E. 1985: Kinetics and importance of the dimerization step in the folding pathway of the beta 2 subunit of Escherichia coli tryptophan synthase Journal of Molecular Biology 182(4): 597-606
Fedorov, A.N.; Friguet, B.; Djavadi Ohaniance, L. 1992: Folding on the ribosome of Escherichia coli tryptophan synthase b subunit nascent chains probed with a conformation-dependent monoclonal antibody Journal of Molecular Biology 228: 1-8
Nishio, K.; Morimoto, Y.; Ishizuka, M.; Ogasahara, K.; Tsukihara, T.; Yutani, K. 2005: Conformational changes in the alpha-subunit coupled to binding of the beta 2-subunit of tryptophan synthase from Escherichia coli: crystal structure of the tryptophan synthase alpha-subunit alone Biochemistry 44(4): 1184-1192
Fedorov, A.N.; Friguet, B.; Djavadi-Ohaniance, L.; Alakhov, Y.B.; Goldberg, M.E. 1992: Folding on the ribosome of Escherichia coli tryptophan synthase beta subunit nascent chains probed with a conformation-dependent monoclonal antibody Journal of Molecular Biology 228(2): 351-358
Onuffer, J.J.; Matthews, C.R. 1987: Proline isomerization in the folding of dihydrofolate reductase from escherichia coli Federation Proceedings 46(6)
Hurle, M.R.; Michelotti, G.A.; Crisanti, M.M.; Matthews, C.R. 1987: Characterization of a slow folding reaction for the alpha subunit of tryptophan synthase Proteins 2(1): 54-63
Crisanti, M.M.; Matthews, C.R. 1981: Characterization of the slow steps in the folding of the alpha subunit of tryptophan synthase Biochemistry 20(9): 2700-2706
Planchenault, T.; Navon, A.; Schulze, A.J.; Goldberg, M.E. 1996: Transient Non-Native Interactions in Early Folding Intermediates do not Influence the Folding Kinetics of Escherichia Coli Tryptophan Synthase 2 Subunits FEBS Journal 240(3): 615-621
Planchenault, T.; Navon, A.; Schulze, A.J. 1996: Transient non-native interactions in early folding intermediates do not influence the folding kinetics of Escherichia coli tryptophan synthase b2 subunits European Journal of Biochemistry 240: 5-21