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The Evaluation of Six Lactose-Based Materials as Direct Compression Tablet Excipients

The Evaluation of Six Lactose-Based Materials as Direct Compression Tablet Excipients

Drug Development and Industrial Pharmacy 14(8): 1023-1040

ISSN/ISBN: 0363-9045

DOI: 10.3109/03639048809151918

Six lactose-based products have been evaluated as direct-compression tableting excipients in a simple formulation. Anhydrous Lactose, NF was the best material overall, with Fast-Flo lactose and Ludipress also being very good. The compaction properties of these products changed to varying degrees when tablets were made on a rotary press instead of a single punch press, and when machine speed was increased on the rotary machine.

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Accession: 062011250

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