A model for iontophoresis incroporating the effect of convective solvent flow
Srinivasan, V.; Higuchi, W.I.
International Journal of Pharmaceutics 60(2): 133-138
1990
ISSN/ISBN: 0378-5173
DOI: 10.1016/0378-5173(90)90298-i
Accession: 062082034
A model for iontophoretic transport is proposed which incorporates the effects of the applied electric field and the induced convective solvent flow, with a linear term to account for the effect of solvent flow on the permeant flux. The predictions of this model are compared with those of a model without the convective solvent flow term. The new model provides a more detailed framework to decouple and understand the interactions of the applied field and the solvent flow effects.