Magnetic resonance imaging of peripheral vascular disease and muscle atrophy in diabetes
John, E. Foster; Robin, A. Damion; William Vennart; Ian, R. Summers; Richard, E. Ellis; Peter Brash; John Tooke
Magnetic Resonance Materials in Physics, Biology and Medicine 2(3): 401-403
Knowledge of the state of tissue hydration in patients suffering from peripheral vascular disease and neuropathy as a result of diabetes is important in their treatment. Further, because magnetic resonance imaging (MRI) is uniquely able to generate information about soft tissues and their water content, it is ideal for studying disorders of this kind. The feet and hands, often affected in diabetes, are ideal for studying fundamental aspects of the disease state and the response of patients to treatment. In this preliminary study, two related areas are reported: the measurement of diffusion coefficients in the finger and the visualization of the distribution of edema and muscle atrophy in the feet of people suffering from diabetes.