Section 63
Chapter 62,658

The 3-untranslated region of the mouse cholesterol 7a-hydroxylase mRNA contains elements responsive to post-transcriptional regulation by bile acids

AGELLON, B. Luis; CHEEMA, K. Sukhinder

Biochemical Journal 328(2): 393-399


ISSN/ISBN: 0264-6021
DOI: 10.1042/bj3280393
Accession: 062657038

Download citation:  

To investigate the importance of the 3'-untranslated region (UTR) of the mouse cholesterol 7alpha-hydroxylase (cyp7) mRNA in post-transcriptional regulation of expression of the cyp7 gene, chimaeric genes encoding mRNA containing the structural sequence of chloramphenicol acetyltransferase (CAT) linked to either the 3'-UTR of the mouse cyp7 mRNA or the SV40 early gene mRNA were constructed. The human cytomegalovirus (CMV) promoter was used to drive the expression of all the chimaeric genes.

PDF emailed within 0-6 h: $19.90