Section 64
Chapter 63,004

Multiple isoforms of the DrosophilaSpätzle protein are encoded by alternatively spliced maternal mRNAs in the precellular blastoderm embryo

DeLotto, Y.; Smith, C.; DeLotto, R.

Molecular Genetics and Genomics 264(5): 643-652


ISSN/ISBN: 1617-4615
DOI: 10.1007/s004380000350
Accession: 063003374

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The spätzle gene is required for proper specification of positional information along the dorsal-ventral axis of the Drosophila embryo and for induction of the innate immune response to fungal infection. It has been shown to encode a precursor of a Nerve Growth Factor-like ligand which is also a member of the cys-knot protein superfamily.

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