Dietary cholesterol affects lipid metabolism in rabbits

Byungrok Min,Ki Chang Nam,Kathleen Mullin,Il Suk Kim…

Food Science and Biotechnology 22(2): 557-565

2013


ISSN/ISBN: 1226-7708
DOI: 10.1007/s10068-013-0114-9
Accession: 064304258

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Abstract
Effects of dietary cholesterol [0 (control), 1, 2, 4, or 8 g cholesterol/kg diet for 12 weeks] on lipid contents and fatty acid compositions in red blood cell (RBC) membranes and plasma of rabbits and pathological changes and lipid oxidation in their livers were determined. Contents of total lipid and unsaturated fatty acids in Rbc membrane and plasma of rabbits fed ≥4 and ≥2 g dosages, respectively, were significantly higher (p 2 times higher (p<0.05) than those fed lower dosages. The results indicated that dietary cholesterol can modify lipid metabolisms of rabbits, including biosynthesis and transportation of lipids and fatty acids and incorporation of fatty acid into Rbc membranes.