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In vitro antimicrobial, antiprotozoal activities and heavy metals toxicity of different parts of Ballota pseudodictamnus (L.) Benth



In vitro antimicrobial, antiprotozoal activities and heavy metals toxicity of different parts of Ballota pseudodictamnus (L.) Benth



Pakistan Journal of Pharmaceutical Sciences 30(6): 2203-2209



The study was done to check the antimicrobial and antiprotozoal activity of different parts of Ballota pseudodictamnus (L.) Benth. These activities were then compared with the heavy metals toxicity of different parts, which plants accumulate in different concentrations in different parts. In in-vitro antileishmanial results ethanolic extract, chloroform and ethyl acetate fractions in roots of Ballota pseudodictamnus (L.) Benth showed antileishmanial activity. The ethanol, n-butanol and ethyl acetate fraction in stem revealed inhibition of amastigote form of leishmania. The ethanolic extract, chloroform, and n-butanol fraction in leaves showed inhibition of leishmanial parasite. In heavy metals study, Chromium was above permissible value in all parts except in leaves. Nickel was above WHO limit in roots. Cadmium and lead were beyond permissible limits in entire plant parts. Results revealed that different parts of the plant have different inhibition properties. So each part of plant should be checked for antimicrobial and antiprotozoal assay separately. It is concluded that various metals accumulates with miscellaneous concentrations in different plant parts.

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Accession: 065257862

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PMID: 29175790


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