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Meroterpenoids from the fruiting bodies of Ganoderma theaecolum



Meroterpenoids from the fruiting bodies of Ganoderma theaecolum



Fitoterapia 125: 273-280



A series of new terminal cyclohexane-type meroterpenoids, ganotheaecoloids A-N (1-6, 8-13, 15, and 16), along with three known ones (7, 14, and 17), were isolated from the dried fruiting bodies of Ganoderma theaecolum. Their chemical structures were identified by using spectroscopic data and computational methods. Biological activity of all the new meroterpenoids against COX-2 was evaluated in vitro, only ganotheaecoloid J (11) was found to have COX-2 inhibitory activity with IC50 value of 9.96μM.

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Accession: 065310014

Download citation: RISBibTeXText

PMID: 29378219

DOI: 10.1016/j.fitote.2018.01.015


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