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Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics



Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics



JAMA 320(5): 499-500



In adults and children prescribed antibiotics, is co-administration of a probiotic associated with a lower risk of symptomatic Clostridium difficile infection without an increase in adverse events? Moderate-quality evidence suggests that probiotics are associated with a lower risk of C difficile infection and very low-quality evidence suggests that probiotics are associated with fewer adverse events vs placebo or no treatment.

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Accession: 065436265

Download citation: RISBibTeXText

PMID: 30027207

DOI: 10.1001/jama.2018.9064


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