+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The impact of high-intensity inspiratory muscle training on exercise capacity and inspiratory muscle strength in heart failure with reduced ejection fraction: a systematic review and meta-analysis



The impact of high-intensity inspiratory muscle training on exercise capacity and inspiratory muscle strength in heart failure with reduced ejection fraction: a systematic review and meta-analysis



Clinical Rehabilitation 32(11): 1482-1492



Inspiratory muscle training (IMT) improves prognostic clinical variables in patients with heart failure. However, the optimal intensity for increasing those outcomes remains unclear. Thus, we aimed to determine whether high-intensity inspiratory muscle training (HIIMT) improves exercise capacity and respiratory muscle strength in patients with heart failure with reduced ejection fraction (HFrEF). We searched for randomized controlled clinical trials at MEDLINE, the Cochrane Central Register of Controlled Trials, the Physiotherapy Evidence Database, SciELO and CINAHL from the earliest date available to May 2018. Primary studies on HIIMT against low-intensity IMT or sham-IMT that evaluated exercise capacity and inspiratory muscle strength were included. Two independent reviewers evaluated the eligibility of studies retrieved from the databases. Disagreements were resolved by discussion or by a third reviewer. Weighted mean difference (WMD), standardized mean difference (SMD) and 95% confidence interval (CI) were estimated by random effect models. Five studies met the eligibility criteria (138 patients). HIIMT improved VO2peak (WMD 2.65 mL kg-1 min-1; 95% CI: 2.2 to 3.1 mL kg-1 min-1), walking tests (SMD 1.71; 95% CI: 0.83 to 2.59) and maximal inspiratory pressure (WMD 16.63 cmH2O; 95% CI: 10.34 to 22.91 cmH2O). The estimate for potential risks of adverse events was not performed because of the low prevalence of reports in primary studies. HIIMT seems to be a useful strategy for improving exercise capacity and inspiratory muscle strength in HFrEF patients.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 065589902

Download citation: RISBibTeXText

PMID: 29984598

DOI: 10.1177/0269215518784345


Related references

High intensity interval training versus moderate intensity continuous training on exercise capacity and quality of life in patients with heart failure with reduced ejection fraction: A systematic review and meta-analysis. International Journal of Cardiology 261: 134-141, 2018

Influence of inspiratory muscle weakness on inspiratory muscle training responses in chronic heart failure patients: a systematic review and meta-analysis. Archives of Physical Medicine and Rehabilitation 95(7): 1398-1407, 2014

Inspiratory work capacity is more severely depressed than inspiratory muscle strength in patients with heart failure: Novel applications for inspiratory muscle training. International Journal of Cardiology 221: 622-626, 2017

Combined Exercise and Inspiratory Muscle Training in Patients With Heart Failure: A SYSTEMATIC REVIEW AND META-ANALYSIS. Journal of Cardiopulmonary Rehabilitation and Prevention 36(6): 395-401, 2016

Inspiratory Muscle Function and Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction. Journal of Cardiac Failure 23(6): 480-484, 2017

Best mode of inspiratory muscle training in heart failure patients: a systematic review and meta-analysis. European Journal of Preventive Cardiology 25(16): 1691-1701, 2018

Inspiratory muscle training improves submaximal exercise capacity in patients with heart failure: a systematic review of randomized controlled trials. International Journal of Cardiology 158(2): 294-296, 2013

Effects of inspiratory muscle training in chronic heart failure patients: A systematic review and meta-analysis. Congenital Heart Disease 13(2): 194-202, 2018

Efficacy of inspiratory muscle training in chronic heart failure patients: a systematic review and meta-analysis. International Journal of Cardiology 167(4): 1502-1507, 2014

Inspiratory muscle training increases inspiratory muscle strength in patients weaning from mechanical ventilation: a systematic review. Journal of PhysioTherapy 57(4): 213-221, 2012

Addition of inspiratory muscle training to aerobic training improves cardiorespiratory responses to exercise in patients with heart failure and inspiratory muscle weakness. American Heart Journal 158(5): 768.E1-7, 2010

Benefits of short inspiratory muscle training on exercise capacity, dyspnea, and inspiratory fraction in COPD patients. International Journal of Chronic Obstructive Pulmonary Disease 3(3): 423-427, 2008

Benefits Of Short Inspiratory Muscle Training On Exercise Capacity, Dyspnea And Inspiratory Fraction (If) In Copd Patients. Chest 132(4): 535-1, 2007

Short period of high-intensity inspiratory muscle training improves inspiratory muscle strength in patients with chronic kidney disease on hemodialysis: a randomized controlled trial. Brazilian Journal of Physical Therapy 2019, 2019

Effects of inspiratory muscle training in patients with heart failure with preserved ejection fraction. European Journal of Preventive Cardiology 21(12): 1465-1473, 2015