Type-1 Seronegative Autoimmune Pancreatitis: a Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto's Disease
Tahir, M.; Singh, A.
Cureus 10(5): E2624
2018
ISSN/ISBN: 2168-8184
PMID: 30027016
Accession: 065646080
Autoimmune pancreatitis (AIP) is very rarely reported in the literature. It is one of the immunoglobulin-G (IgG) related diseases that commonly presents with abdominal pain, mass, jaundice, and weight changes. The disease also has extrapancreatic manifestations, of which the most common is autoimmune sclerosing cholangitis. We report a case of autoimmune pancreatitis that was further found to be associated with Hashimoto's thyroiditis and sclerosing cholangitis. The clinical manifestations vary and it is important to exclude pancreatic malignancy before diagnosing any patient with AIP. Although further studies need to be done, currently the treatment of choice is steroid therapy. Physicians should also screen patients for other autoimmune diseases to rule out any concern.