+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Urological outcomes following pelvic exenteration for advanced pelvic cancer are not inferior to those following radical cystectomy

Urological outcomes following pelvic exenteration for advanced pelvic cancer are not inferior to those following radical cystectomy

Anz Journal of Surgery 88(9): 896-900

Pelvic exenteration (PE) for locally advanced pelvic malignancy requires a multi-disciplinary approach and is associated with significant morbidity. Urinary reconstruction forms a major component of this procedure. The aim of the study is to review the urological outcomes following PE in a newly established pelvic oncology unit, to compare with those following radical cystectomy (RC) for bladder cancer. Patients were identified from prospectively maintained PE and bladder cancer databases, inclusive of all cases performed between January 2012 and December 2016. Those without urinary reconstructions and follow-up durations of less than 3 months were excluded. The outcomes of PE and RC cases were compared, stratifying surgical complications using the Clavien-Dindo classification. Statistical significance was defined as P < 0.05. There were 22 PE cases and 27 RC cases. The median age at surgery was 56 and 65 years, with a median follow-up of 11.7 and 19.8 months, in the PE and RC groups, respectively. Urinary reconstructions comprised n = 20 (91%) conduit diversions and n = 2 (9%) ureteral reimplantations in the PE group, and n = 5 (19%) orthotopic bladder substitutes and n = 22 (81%) ileal conduits in the RC group. The 30-day urological complication rate was 23% in the PE group (n = 4 Clavien-Dindo Grade 1-2, and n = 1 Grade 3) versus 11% in the RC group (n = 1 Grade 1-2, and n = 2 Grade 3), P = 0.801. There were no Grade 4-5 complications in this series. The urological outcomes following PE in complex pelvic oncology are reasonable and not inferior to those after primary RC alone.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 065655698

Download citation: RISBibTeXText

PMID: 29895098

DOI: 10.1111/ans.14689

Related references

Outcomes of Pelvic Exenteration with en Bloc Partial or Complete Pubic Bone Excision for Locally Advanced Primary or Recurrent Pelvic Cancer. Diseases of the Colon and Rectum 59(9): 831-835, 2017

Urological complications after cystectomy as part of pelvic exenteration are higher than that after cystectomy for primary bladder malignancy. Journal of Surgical Oncology 115(3): 307-311, 2016

Pelvic Exenteration Surgery: The Evolution of Radical Surgical Techniques for Advanced and Recurrent Pelvic Malignancy. Diseases of the Colon and Rectum 60(7): 745-754, 2017

Clinical outcomes of pelvic exenteration for locally advanced primary or recurrent non-colorectal pelvic malignancies. Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(12): 2433-2436, 2014

A prospective evaluation of surgical outcomes of laparoscopic transperitoneal radical cystectomy/anterior pelvic exenteration: our surgical technique and experience. Central European Journal of Urology 70(2): 214-215, 2017

Pelvic exenteration advanced neopl pelvic cancer therapy human surgery. Cleveland Clinic Quarterly 36(1): 1-8, 1969

Outcome of Pelvic Exenteration for Locally Advanced Cancer of the Pelvic Organs. Voprosy Onkologii 61(3): 448-451, 2015

Total pelvic exenteration in the treatment of advanced pelvic cancer. Chirurgia 102(2): 143-154, 2007

Sacral resection with pelvic exenteration for advanced primary and recurrent pelvic cancer: a single-institution experience of 100 sacrectomies. Diseases of the Colon and Rectum 57(10): 1153-1161, 2014

Total pelvic exenteration for pelvic recurrence after advanced epithelial ovarian cancer--A case report and literature review. Journal of Medicine and Life 8(3): 263-265, 2016

Prognostic role of mesenteric lymph nodes involvement in patients undergoing posterior pelvic exenteration during radical or supra-radical surgery for advanced ovarian cancer. Archives of Gynecology and Obstetrics 297(4): 997-1004, 2018

Results of radical cystectomy and pelvic lymphadenectomy for bladder cancer with pelvic node metastases. Urologia Internationalis 57(1): 27-31, 1996

Outcomes of pelvic exenteration for recurrent or primary locally advanced colorectal cancer. Annals of Surgical Treatment and Research 89(3): 131-137, 2015

Outcomes of pelvic exenteration for recurrent and primary locally advanced rectal cancer. International Journal of Surgery 48: 69-73, 2017

Pelvic exenteration with en bloc resection of the pelvic sidewall and intraoperative electron beam radiotherapy with Mobetron ® for locally advanced rectal cancer. Techniques in Coloproctology 21(6): 493-495, 2017