EurekaMag
+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Color Doppler imaging evaluation of blood flow parameters in ophthalmic and posterior ciliary arteries and optic nerve diameter in chronic optic neuritis in multiple sclerosis patients


Color Doppler imaging evaluation of blood flow parameters in ophthalmic and posterior ciliary arteries and optic nerve diameter in chronic optic neuritis in multiple sclerosis patients



Multiple Sclerosis and Related Disorders 27: 195-199



ISSN/ISBN: 2211-0348

PMID: 30408757

DOI: 10.1016/j.msard.2018.10.001

Optic neuritis (ON) is a common clinical manifestation of Multiple Sclerosis (MS), which is associated with reduced visual acuity, blurred vision, blindness and retro-bulbar pain. In several studies, specific relations between optic nerve diameter and hemodynamics of the eye bulb arteries with ON have been reported. However, no consensus has been reached in this regard. We aim at determining the alterations in optic nerve diameter and eye bulb arteries hemodynamics in ON in MS patients. This case-control study includes 40 patients, who at least had experienced one phase of ON, in one of their eyes. To measure hemodynamics of arteries in the affected eyes, a color Doppler imaging was performed and end diastolic velocity (EDV), peak systolic velocity (PSV), peripheral resistance indices i.e. resistance index (RI) and pulsatile index (PI) were measured in posterior ciliary artery (PCA) and ophthalmic artery (OA). Also, optic nerve diameter was measured using sonography. Non-affected eyes of these patients were considered as control group. There were no significant differences in EDV, PSV, RI and PI in PCA and OA. The mean optic nerve diameter in the affected eyes was 4.73 mm, whereas, it was 4.31 mm in unaffected eyes, which was significantly different (P = .02). These results indicate that there is a significant relation between eye involvement and increased optic nerve diameter in MS patients with chronic ON. While, there were no significant relations in EDV, PSV, RI and PI in PCA and OA comparing two groups.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 065732153

Download citation: RISBibTeXText

Related references

Colour Doppler imaging evaluation of blood flow parameters in the ophthalmic artery in acute and chronic phases of optic neuritis in multiple sclerosis. Acta Ophthalmologica 87(1): 65-70, 2009

Assessment of blood flow velocity in eyeball arteries in multiple sclerosis patients with past retrobulbar optic neuritis in color Doppler ultrasonography. Klinika Oczna 109(4-6): 183-186, 2007

Acute Optic Neuritis in Multiple Sclerosis: Evaluation of Hemodynamics in the Ophthalmic Artery with Colour Doppler Imaging. Neuro-Ophthalmology 29(4): 161-164, 2005

Multiple sclerosis and optic nerve: an analysis of retinal nerve fiber layer thickness and color Doppler imaging parameters. Eye 28(10): 1206-1211, 2014

Color Doppler imaging in optic neuritis with multiple sclerosis. Graefe's Archive for Clinical and Experimental Ophthalmology 242(12): 990-994, 2004

The diagnostic performance of ultrasonographic optic nerve sheath diameter and color Doppler indices of the ophthalmic arteries in detecting elevated intracranial pressure. Clinical Neurology and Neurosurgery 141: 82-88, 2016

Comparative evaluation of blood flow velocity and pulsation curve in the posterior ciliary arteries supplying the choroid and the anterior part of the optic nerve. Klinika Oczna 93(7-8): 191-193, 1991

Diffusion-weighted imaging of the human optic nerve: a new approach to evaluate optic neuritis in multiple sclerosis. Magnetic Resonance in Medicine 38(3): 484-491, 1997

Color doppler imaging of the internal ophthalmic and long posterior ciliary arteries in the dog. Turk Veterinerlik ve Hayvanclk Dergisi 27(5): 1219-1224, 2003

Optic nerve demyelination induced by human serum: patients with multiple sclerosis or optic neuritis and normal subjects. Neurology 35(10): 1438-1442, 1985

Ultrasound findings of the optic nerve and its arterial venous system in multiple sclerosis patients with and without optic neuritis vs healthy controls. Perspectives in Medicine 1(1-12): 381-384, 2012

Visual evoked potentials, contrast sensitivity and color perception in patients with optic nerve neuritis and multiple sclerosis. Klinische Monatsblatter für Augenheilkunde 179(3): 161-168, 1981

Acute optic neuritis: combined immunological markers and magnetic resonance imaging predict subsequent development of multiple sclerosis. The Optic Neuritis Study Group. Journal of the Neurological Sciences 155(1): 44-49, 1998

The correlation of changes of the optic nerve diameter in the acute retrobulbar neuritis with the brain changes in multiple sclerosis. Collegium Antropologicum 29(2): 633-636, 2005

Retinal nerve fibre layer evaluation in multiple sclerosis patients with and without optic neuritis. Acta Ophthalmologica 97(4): E662-E663, 2019