+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Dissipation behavior and dietary risk assessment of lambda-cyhalothrin, thiamethoxam and its metabolite clothianidin in apple after open field application



Dissipation behavior and dietary risk assessment of lambda-cyhalothrin, thiamethoxam and its metabolite clothianidin in apple after open field application



Regulatory Toxicology and Pharmacology 101: 135-141



The dissipation dynamics and residue amounts of lambda-cyhalothrin, thiamethoxam and clothianidin in apple were investigated by using rapid resolution liquid chromatography triple quadrupole mass spectrometer (RRLC-MS/MS) and gas chromatography mass spectrometry (GC-MS). The developed method performed satisfactory recoveries of 88%-105% and the limit of quantitation (LOQ) was 0.01 mg kg-1. The suspension concentrate (SC) formulation of lambda-cyhalothrin and thiamethoxam was applied on apple field in accordance with good agricultural practice (GAP). The half-lives of two pesticides ranged from 7.01 d to 17.3 d and the terminal residues were <0.01-0.21 mg kg-1. Based on the Chinese dietary pattern, the dietary risk of lambda-cyhalothrin and total thiamethoxam were predicted by comparing intake amounts with the toxicological data, namely acceptable daily intake (ADI) and acute reference dose (ARfD). The chronic and acute risk quotients were 0.1080-0.4463 and 0.0008-0.2005, respectively, which showed negligible risk for general consumers. The pre-harvest interval (PHI) of 21 d was suggested for the formulation in compliance with maximum residue limit (MRL) and dietary risk assessment, meanwhile, the MRL of 0.1 mg kg-1 was recommended for thiamethoxam in apple. These results were vital for guiding reasonable usage of two insecticides and for approval of formulation use.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 065757182

Download citation: RISBibTeXText

PMID: 30445137

DOI: 10.1016/j.yrtph.2018.11.003


Related references

Determination of the residue dynamics and dietary risk of thiamethoxam and its metabolite clothianidin in citrus and soil by LC-MS/MS. Journal of Environmental Science and Health. Part. B Pesticides Food Contaminants and Agricultural Wastes 54(4): 326-335, 2019

Dissipation behaviour and dietary risk assessment of boscalid, triflumizole and its metabolite (FM-6-1) in open-field cucumber based on QuEChERS using HPLC-MS/MS technique. Journal of the Science of Food and Agriculture 98(12): 4501-4508, 2018

Risk assessment of lambda-cyhalothrin on aquatic organisms in paddy field in China. Regulatory Toxicology and Pharmacology 48(1): 69-74, 2007

Spinach or amaranth contains highest residue of metalaxyl, fluazifop-P-butyl, chlorpyrifos, and lambda-cyhalothrin on six leaf vegetables upon open field application. Journal of Agricultural and Food Chemistry 61(9): 2039-2044, 2013

Dissipation kinetics and assessment of processing factor for chlorpyrifos and lambda-cyhalothrin in cardamom. Environmental Monitoring and Assessment 185(6): 5277-5284, 2013

Dissipation behavior, residue distribution and dietary risk assessment of field-incurred boscalid and pyraclostrobin in grape and grape field soil via MWCNTs-based QuEChERS using an RRLC-QqQ-MS/MS technique. Food Chemistry 274: 291-297, 2019

Effect of thiamethoxam on cockroach locomotor activity is associated with its metabolite clothianidin. Pest Management Science 66(12): 1351-1359, 2010

Oral acute toxicity of imidacloprid, thiamethoxam and clothianidin in eared doves: A contribution for the risk assessment of neonicotinoids in birds. Science of the Total Environment 650(Pt 1): 1216-1223, 2019

Quantitative weight of evidence assessment of risk to honeybee colonies from use of imidacloprid, clothianidin, and thiamethoxam as seed treatments: a postscript. Journal of Toxicology and Environmental Health. Part B Critical Reviews 20(6-7): 383-386, 2017

Persistence behaviour of thiamethoxam and lambda cyhalothrin in transplanted paddy. Bulletin of Environmental Contamination and Toxicology 85(4): 419-422, 2010

Accumulation and toxicity of thiamethoxam and its metabolite clothianidin to the gonads of Eremias argus. Science of the Total Environment 667: 586-593, 2019

Dissipation and residue behavior of emamectin benzoate on apple and cabbage field application. Ecotoxicology and Environmental Safety 78: 260-264, 2012

Efficacy of thiamethoxam in the control of Empoasca vitis in comparison with lambda-cyhalothrin, abamectin, indoxacarb and chlorpyrifos. Giornate Fitopatologiche 2006, Riccione RN, 27-29 marzo 2006 Atti, volume primo: 111-116, 2006

Dissipation, terminal residues and risk assessment of fluopicolide and its metabolite in cucumber under field conditions. Environmental Monitoring and Assessment 187(11): 698, 2015

Dissipation kinetics and risk assessment of thiamethoxam and dimethoate in mango. Environmental Monitoring and Assessment 188(3): 165, 2016