+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Food Allergy: A Comprehensive Population-Based Cohort Study

Food Allergy: A Comprehensive Population-Based Cohort Study

Mayo Clinic Proceedings 93(10): 1423-1430

Label="OBJECTIVE">To determine the incidence and temporal trends of food allergies.Label="PATIENTS AND METHODS">We performed a historical cohort study to describe the epidemiology of food allergies among residents of all ages in Olmsted County, Minnesota, during a 10-year period from January 2, 2002, through December 31, 2011, using the Rochester Epidemiology Project database. Overall incidence and trends in biannual incidence rates over time were evaluated.Label="RESULTS">During the 10-year study period, 578 new cases of food allergies were diagnosed. The average annual incidence rate was significantly higher among males compared with females (4.1 [95% CI, 3.6-4.5] vs 3.0 [95% CI, 2.7-3.4]; P<.001; per 10,000 person-years; 3.6 per 10,000 person-years overall). The pediatric incidence rate of food allergy increased from 7.0 (95% CI, 6.2-8.9) to 13.3 (95% CI, 10.9-15.7) per 10,000 person-years between the 2002-2003 and 2006-2007 calendar periods and then stabilized at 12.5 and 12.1 per 10,000 person-years in the last 2 calendar periods. Milk, peanut, and seafood were the most common allergen in infancy, in children between ages 1 and 4 years, and in the adult population, respectively.Label="CONCLUSION">This is one of the first population-based studies to examine the temporal trends of food allergies. The incidence of food allergies increased markedly between 2002 and 2009, with stabilization afterward. Additional longitudinal studies are warranted to assess for epidemiological evidence of changes in food allergy incidence with changing recommendations for allergenic food introduction.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 065790013

Download citation: RISBibTeXText

PMID: 30286830

DOI: 10.1016/j.mayocp.2018.05.031

Related references

The South African Food Sensitisation and Food Allergy population-based study of IgE-mediated food allergy: validity, safety, and acceptability. Annals of Allergy Asthma and Immunology 115(2): 113-119, 2015

Which infants with eczema are at risk of food allergy? Results from a population-based cohort. Clinical and Experimental Allergy 45(1): 255-264, 2015

Which Infants With Eczema Are at Risk for Food Allergy? Results From a Population-Based Cohort. Pediatrics 136(Suppl.): S240-S241, 2015

The impact of family history of allergy on risk of food allergy: a population-based study of infants. International Journal of Environmental Research and Public Health 10(11): 5364-5377, 2013

Cohort Profile: The HealthNuts Study: Population prevalence and environmental/genetic predictors of food allergy. International Journal of Epidemiology 44(4): 1161-1171, 2015

Assessment of Allergy to Milk, Egg, Cod, and Wheat in Swedish Schoolchildren: A Population Based Cohort Study. Plos one 10(7): E0131804, 2015

Recorded Penicillin Allergy and Risk of Mortality: a Population-Based Matched Cohort Study. Journal of General Internal Medicine 34(9): 1685-1687, 2019

Atopic dermatitis at preschool age and contact allergy in adolescence: a population-based cohort study. British Journal of Dermatology 180(4): 782-789, 2019

Timing of eczema onset and risk of food allergy at 3 years of age: A hospital-based prospective birth cohort study. Journal of Dermatological Science 84(2): 144-148, 2016

The natural history and clinical predictors of egg allergy in the first 2 years of life: a prospective, population-based cohort study. Pediatrics 134(Suppl. 3): S150-S150, 2014

Prevalence of immediate-type food allergy in Korean schoolchildren: a population-based study. Allergy and Asthma Proceedings 33(6): 481-487, 2013

Formula and breast feeding in infant food allergy: A population-based study. Journal of Paediatrics and Child Health 52(4): 377-384, 2016

SKARP--A population-based cohort study of childhood food-associated symptoms perceived by parents and food allergies diagnosed by physicians: design, methods and participation. Scandinavian Journal of Public Health 39(2): 194-202, 2011

The HealthNuts population-based study of paediatric food allergy: validity, safety and acceptability. Clinical and Experimental Allergy 40(10): 1516-1522, 2010

Parent-reported prevalence of food allergy in Mexican schoolchildren: A population-based study. Allergologia et Immunopathologia 44(6): 563-570, 2016