EurekaMag
+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

The Potential Role of Dietary Antioxidant Capacity in Preventing Age-Related Macular Degeneration


The Potential Role of Dietary Antioxidant Capacity in Preventing Age-Related Macular Degeneration



Journal of the American College of Nutrition 38(5): 424-432



ISSN/ISBN: 0731-5724

PMID: 30570376

DOI: 10.1080/07315724.2018.1538830

Objectives: Age-related macular degeneration (AMD) is a progressive disorder among people aged ≥50 years. Some dietary factors associated with the susceptibility to AMD include dietary glycemic index and glycemic load, as well as intake of antioxidants and other nutrients, such as vitamins, minerals, and dietary fatty acids. Methods: This case-control study was conducted between July 2015 and February 2016 on 100 case subjects with AMD and 100 healthy controls without AMD. The participants were recruited from the Department of Ophthalmology of Hacettepe University Hospitals in Ankara, Turkey. Dietary intake was estimated from a 3-day food intake record and food frequency questionnaire, and anthropometric measurements were recorded. The relationship between nutritional factors and AMD was assessed using logistic regression. Results: Dietary total antioxidant intake of AMD group was found to be lower (p < 0.05) than that of healthy individuals. In a multivariate analysis, smoking, daily red meat intake, omega-6 intake, and higher glycemic index were identified as risk factors for AMD development. Meanwhile, daily fruit intake, daily fish intake, omega-3 intake, and zinc intake were associated with a protective effect. However, no difference was found in dietary total antioxidant capacity. Conclusions: In this study, a high dietary intake of carotenoids, vitamins C and E, zinc, and omega-3, as well as maintaining optimal waist circumference, were found to substantially reduce the risk of developing AMD in people aged >50 years. By contrast, in addition to smoking and old age, obesity, high red meat intake, and omega-6 intake might increase the risk of developing AMD. Therefore, a better understanding of nutritional risk factors is necessary for preventing AMD.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 066025204

Download citation: RISBibTeXText

Related references

The potential role of dietary xanthophylls in cataract and age-related macular degeneration. Journal of the American College of Nutrition 19(5 Suppl): 522s-527s, 2000

Metabolism of dietary carotenoids and their potential role in prevention of cancer and age-related macular degeneration. Shibanoto, T, Terao, J, Osawa, T ACS Symposium Series; Functional foods for disease prevention, I: Fruits, vegetables, and teas 71-85, 1998

Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. Cochrane Database of Systematic Reviews 2012(6): Cd000253, 2012

Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. Cochrane Database of Systematic Reviews 2008(1): Cd000253, 2008

Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. Cochrane Database of Systematic Reviews 7: Cd000253, 2017

Antioxidant vitamin and mineral supplementation for preventing age-related macular degeneration. Cochrane Database of Systematic Reviews 2000(2): Cd000253, 2000

A review of the evidence for dietary interventions in preventing or slowing the progression of age-related macular degeneration. Ophthalmic and Physiological Optics: the Journal of the British College of Ophthalmic Opticians 34(4): 390-396, 2014

Smoking, antioxidant supplementation and dietary intakes among older adults with age-related macular degeneration over 10 years. Plos one 10(3): E0122548, 2015

Potential value of antioxidant-rich foods in slowing age-related macular degeneration. Archives of Ophthalmology 124(9): 1339-1340, 2006

Benefits, Potential Harms, and Optimal Use of Nutritional Supplementation for Preventing Progression of Age-Related Macular Degeneration. Annals of PharmacoTherapy 51(3): 264-270, 2017

BSCN: bidirectional symmetric cascade network for retinal vessel segmentation. Bmc Medical Imaging 20(1): 20, 2020

Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration. American Journal of Clinical Nutrition 83(6 Suppl): 1494s-1498s, 2006

Potential role of dietary n3 fatty acids in the prevention of dementia and macular degeneration. The American Journal of Clinical Nutrition 83(6): 1494S-1498S, 2006

The potential effect of population development, smoking and antioxidant supplementation on the future epidemiology of age-related macular degeneration in Switzerland. Klinische Monatsblatter für Augenheilkunde 225(5): 376-379, 2008

Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD). Biogerontology 14(5): 461-482, 2013