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Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide

Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide

Nutrients 11(2)

Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H₂S), an endogenous, gaseous, signaling transmitter, has also been shown to be involved in the regulation of inflammation. Recent studies have shown that sulfur-containing compounds from garlic have beneficial effects in attenuating outcomes associated with cardiovascular disease and inflammation by a mechanism that may be related to the H₂S signaling pathway. In this review, we summarize the main functions of glutathione (GSH), garlic derivatives and H₂S and their role in the immune response and impact on health and disease.

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Accession: 066446189

Download citation: RISBibTeXText

PMID: 30704060

DOI: 10.3390/nu11020295

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