+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Preoperative molecular testing on fine-needle aspiration in precision management of thyroid cancer



Preoperative molecular testing on fine-needle aspiration in precision management of thyroid cancer



Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 54(1): 58-61



本文围绕甲状腺癌诊治中有争议的热点问题,系统介绍了目前国内外几种常用的分子检测方法,特别是基因突变及融合检测,在甲状腺结节的术前诊断和甲状腺癌的预后评估中的重要意义。对于穿刺细胞学诊断不确定的甲状腺结节,不同的分子检测方法各有其优点和不足,其中DNA检测,特别是基于二代测序技术的多基因联合检测具有较好的灵敏度和特异度。除了用于诊断,它还可以检出与肿瘤预后有关的基因变异,如BRAF(V600E)突变和TERT启动子突变等,具有较广阔的应用前景。.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 066446299

Download citation: RISBibTeXText

PMID: 30704174


Related references

BRAF mutation testing of thyroid fine-needle aspiration biopsy specimens for preoperative risk stratification in papillary thyroid cancer. Journal of Clinical Oncology 27(18): 2977-2982, 2009

Preoperative precision value of thyroid fine needle aspiration in thyroid surgical resection candidates. Saudi Medical Journal 25(12): 2034-2036, 2005

Molecular Testing for miRNA, mRNA, and DNA on Fine-Needle Aspiration Improves the Preoperative Diagnosis of Thyroid Nodules With Indeterminate Cytology. Journal of Clinical Endocrinology and Metabolism 100(7): 2743-2750, 2015

Large-needle aspiration biopsy for the preoperative selection of palpable thyroid nodules diagnosed by fine-needle aspiration as a microfollicular nodule or suspected cancer. American Journal of Clinical Pathology 113(6): 872-877, 2000

The indeterminate thyroid fine-needle aspiration: experience from an academic center using terminology similar to that proposed in the 2007 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Cancer 117(3): 195-202, 2009

The Indeterminate Thyroid Fine-Needle Aspiration: Experience From an Academic Center Using Terminology Similar to That Proposed in the 2007 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Yearbook of Pathology and Laboratory Medicine 2010: 205-206, 2010

The value of thyroid peroxidase immunohistochemistry for preoperative fine-needle aspiration diagnosis of the follicular variant of papillary thyroid cancer. Surgery (St Louis) 126(6): 1200-1204, 1999

Fine needle aspiration biopsy in the preoperative management of patients with thyroid nodules. Anticancer Research 18(5b): 3741-3745, 1998

Is there still a role for thyroid scintigraphy in the workup of a thyroid nodule in the era of fine needle aspiration cytology and molecular testing?. F1000research 5, 2016

HMGA2 Gene Expression in Fine-needle Aspiration Samples of Thyroid Nodules as a Marker for Preoperative Diagnosis of Thyroid Cancer. Applied Immunohistochemistry and Molecular Morphology 2018, 2018

Aspiration needle biopsy in preoperative selection of thyroid nodules defined at fine-needle aspiration as microfollicular lesions. American Journal of Clinical Oncology 22(1): 65-69, 1999

Aspiration needle biopsy refines preoperative diagnosis of thyroid nodules defined at fine needle aspiration as microfollicular nodule. Biomedicine & Pharmacotherapy. 50(8): 325-328, 1996

The combination of aspiration needle biopsy with fine needle aspiration in preoperative selection of thyroid tumors. Biomedicine & Pharmacotherapy 47(6-7): 245, 1993

Fine needle aspiration biopsy-RT-PCR molecular analysis of thyroid nodules: a useful preoperative diagnostic tool. Minerva Endocrinologica 31(2): 179-182, 2006

Molecular detection of PPAR gamma rearrangements and thyroid carcinoma in preoperative fine-needle aspiration biopsies. Endocrine Pathology 19(3): 166-174, 2008