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Normalization in axillary lymph node management after neoadjuvant therapy for breast cancer



Normalization in axillary lymph node management after neoadjuvant therapy for breast cancer



Zhonghua Wai Ke Za Zhi 57(2): 97-101



新辅助治疗使部分乳腺癌患者的原发灶和腋窝转移淋巴结降期,为乳腺癌外科个体化治疗带来了新的挑战和机遇。前者为不可手术和不适合保留乳房手术的乳腺癌患者提供了手术的可能和保留乳房的机会,后者为前哨淋巴结活检代替腋窝淋巴结清扫提供了可能。但采用早期乳腺癌前哨淋巴结活检的技术和方法,新辅助治疗后前哨淋巴结活检的发现率和假阴性率难以达到临床要求。因此,新辅助治疗后的前哨淋巴结活检应由拥有先进的影像学设备、具有丰富的前哨淋巴结活检经验、能够对新辅助治疗前后的腋窝状况进行准确评估和对新辅助治疗前转移淋巴结进行标记的团队实施,适应证应严格限定在cN0期降至ycN0期和cN1期降至ycN0期的患者,尤其是对新辅助治疗后腋窝淋巴结转阴的病例,必须满足双示踪剂(蓝染料和放射性核素)、切除前哨淋巴结数目≥3枚、靶向腋窝淋巴结切除术3个条件,才能保证新辅助治疗后前哨淋巴结活检的安全正确实施。.

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Accession: 066446330

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PMID: 30704211


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