+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Possibilities for rationally exploiting co-evolution in addressing resistance to insecticides, and beyond

Possibilities for rationally exploiting co-evolution in addressing resistance to insecticides, and beyond

Pesticide Biochemistry and Physiology 151: 18-24

Certain biorational chemical agents used against insect pests impact essential stages or processes in insect life cycles when applied for pest management. Development of resistance to these agents, while involving maintenance of the natural role of the chemical agent, frequently requires the evolution of a new chemical structure by the resistant organism. When considering the process of resistance development, one could theoretically consider biorational structural determination rather than the less predictable or feasible generation of a novel replacement insecticide. At first consideration, this process might exclude toxicants such as typical pest control agents and rather be a phenomenon reserved principally for signalling processes such as are fulfilled by pheromones and other semiochemicals. However, because there is a unique co-evolutionary relationship between chemical defence and the physiology of the antagonistic organism, this process can be further explored for potential to overcome resistance to toxins. Given further consideration, newly evolved chemical defences may rationally provide options for new resistance-defeating chemistry. This review therefore discusses the potential for overcoming insecticide resistance through targeted application of this approach. Potential for use of a similar approach to counteract fungicide and herbicide resistance is also considered. Furthermore, the possible applications of this approach to address drug or pharmaceutic resistance are also considered.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 066446789

Download citation: RISBibTeXText

PMID: 30704708

DOI: 10.1016/j.pestbp.2018.03.007

Related references

Viral resistance evolution fully escapes a rationally designed lethal inhibitor. Molecular Biology and Evolution 26(9): 2041-2046, 2009

Rationally addressing the opiate drug problem. West Virginia Medical Journal 112(6): 8, 2018

Geological-technical mapping for evaluating and rationally exploiting clay from the Tertiary Piemonte Basin. International Geological Congress, Abstracts = Congres Geologique International, Resumes 27(Vol, 1984

Resistance of Colorado potato beetle to insecticides and possibilities to control it. Agrokhimiya 0(7-8): 144-150, 1994

Exploiting evolution to treat drug resistance: combination therapy and the double bind. Molecular Pharmaceutics 9(4): 914-921, 2012

Exploiting pathogens and their impact on fitness costs to manage the evolution of resistance to Bacillus thuringiensis. Journal of applied ecology 44(4): 768-780, 2007

Current concepts of resistance of arthropods to insecticides mechanisms of its formation and possibilities of delay in their continuous use. Meditsinskaya Parazitologiya i Parazitarnye Bolezni 51(1): 28-32, 1982

Current concepts of arthropod resistance to insecticides, the mechanisms of its formation and the possibilities of delaying its development during prolonged insecticide use. Meditsinskaia Parazitologiia i Parazitarnye Bolezni 51(1): 28-32, 1982

Evolution of resistance in the presence of 2 insecticides. Genetics 109(4): 761-784, 1985

Genetics and evolution of resistance to insecticides. Biological Journal of the Linnean Society 27(2): 103-112, 1986

Evolution of resistance in the presence of two insecticides. Genetics 109(4): 761-783, 1985

Addressing resistance evolution in Pseudomonas aeruginosa using pharmacodynamic modelling: application to meropenem dosage and combination therapy. Clinical Microbiology and Infection 13(6): 579-585, 2007

Neonicotinoid insecticides: historical evolution and resistance mechanisms. Advances in Experimental Medicine and Biology 683: 75-83, 2010

Evolution of resistance to pyrethroid insecticides in Musca domestica. Pest Management Science 73(4): 716-722, 2016

The dominance levels and evolution of insect resistance to insecticides. Chinese Bulletin of Entomology 44(2): 186-190, 2007