+ Translate
+ Most Popular
The pigeon tick (Argas reflexus): its biology, ecology, and epidemiological aspects
Prevalence of hemoglobin abnormalities in Kebili (Tunisian South)
Lipogranuloma: a preventable complication of dacryocystorhinostomy
Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency
Bees from the Belgian Congo. The acraensis group of Anthophora
Placing gingival retraction cord
Total serum IgE, allergy skin testing, and the radioallergosorbent test for the diagnosis of allergy in asthmatic children
Acariens plumicoles Analgesoidea parasites des oiseaux du Maroc
Injuries of terminal phalanges of the fingers in children
Biology of flowering and nectar production in pear (Pyrus communis)
Das Reliktvorkommen der Aspisviper (Vipera aspis L.) im Schwarzwald
Hydrological modelling of drained blanket peatland
Pathologic morphology and clinical significance of the anomalous origin of the left circumflex coronary artery from the right coronary artery. General review and autopsy analysis of 30 cases
Cyto genetic analyses of lymphocyte cultures after exposure to calcium cyclamate
Axelrodia riesei, a new characoid fish from Upper Rio Meta in Colombia With remarks concerning the genus Axelrodia and description of a similar, sympatric, Hyphessobrycon-species
Favorable evolution of a case of tuberculosis of pancreas under antibiotic action
RIFM fragrance ingredient safety assessment, Valencene, CAS Registry Number 4630-07-3
Parenteral microemulsions: an overview
Temperate pasture: management for grazing and conservation
Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation
Thermal expansion and cracking of three confined water-saturated igneous rocks to 800C
Revision of the genera of the tribe Stigmoderini (Coleoptera: Buprestidae) a discussion of phylogenetic relationships
Anal tuberculosis. Report of a case
Gastric tuberculosis in the past and present
Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring

Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China

Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China

Iranian Journal of Public Health 48(4): 681-687

ISSN/ISBN: 2251-6085

PMID: 31110978

To investigate the clinical significance of monitoring the coagulation indexes, immune factors and inflammatory factors in pregnancy-induced hypertension syndrome (PIH). 90 pregnant women with PIH admitted in Weihaiwei People's Hospital of Shandong Province, China from 2016 to 2017 were collected, including 45 cases in mild-moderate group and 45 cases in severe group. Another 45 normal pregnant women at the same period were selected as control group. The immune indexes, four index signs of coagulation bloods and serum inflammatory factors in three groups of subjects were determined. The levels of complement 3 (C3), complement 4 (C4), immunoglobulin A (IgA), immunoglobulin G (IgG) and immunoglobulin M (IgM) were successively increased in severe PIH group, mild-moderate PIH group and normal pregnancy group (P<0.05). Compared with those in normal pregnancy group, the levels of PT, APTT and TT were significantly decreased and Fib levels were significantly increased in PIH groups (P<0.05). Compared with those in normal pregnant women, the levels of TNF-α and IL-6 in pregnant women with PIH were significantly increased (P<0.05), and the changes in severe PIH group were more obvious than those in mild-moderate group. Pregnant women with PIH are in a hypercoagulable state and have a higher risk of thrombus and secondary hyperfibrinolysis. Immune factors and inflammatory factors are also associated with the occurrence and development of the disease. Monitoring the changes in coagulation indexes and levels of immune factors and inflammatory factors provide an important reference value for clinical treatment and prevention of complications.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 066803841

Download citation: RISBibTeXText

Related references

Clinical Significance of Coagulation Indicators and their Correlation with Inflammatory Factors in Critical Patients with Thromboembolism. Zhongguo Shi Yan Xue Ye Xue Za Zhi 25(6): 1776-1780, 2017

Change and clinical significance of coagulation, anticoagulation and fibrinolysis indexes in pregnancy with chronic hepatitis B patients. Zhonghua Gan Zang Bing Za Zhi 20(12): 942-944, 2012

Risk factors and potential protective factors of pregnancy-induced hypertension in China: A cross-sectional study. Journal of Clinical Hypertension 21(5): 618-623, 2019

Clinical spectrum, risk factors and outcome of immune reconstitution inflammatory syndrome in patients with tuberculosis-HIV coinfection. Antiviral Therapy 17(5): 841-848, 2012

Role and clinical significance of coagulation and inflammatory factors in moderate and severe ovarian endometriosis. Zhonghua Fu Chan Ke Za Zhi 53(3): 167-171, 2018

Vascular Endothelial Growth Factor expression in peripheral blood of patients with pregnancy induced hypertension syndrome and its clinical significance. Pakistan Journal of Medical Sciences 30(3): 634-637, 2014

Detection of circulating immune complexes in the serum of pregnant patients in normal pregnancy and in pregnancy-induced hypertension using precipitation by polyethylene glycol. Zentralblatt für Gynakologie 108(4): 238-245, 1986

Detection of antineutrophil cytoplasmic autoantibodies in pregnancy induced hypertension and its clinical significance. Zhonghua Fu Chan Ke Za Zhi 34(12): 715-716, 1999

Screening program and risk factors on pregnancy-induced hypertension syndrome. Zhonghua Liu Xing Bing Xue Za Zhi 25(10): 845-847, 2004

The clinical pattern, prevalence, and factors associated with immune reconstitution inflammatory syndrome in Ugandan children. Aids 24(13): 2009-2017, 2010

The efficacy of ropivacaine and bupivacaine in the caesarean section and the effect on the vital signs and the hemodynamics of the lying-in women. Saudi Journal of Biological Sciences 26(8): 1991-1994, 2019

Abnormality of blood coagulation indexes in patients with de novo acute leukemia and its clinical significance. Zhongguo Shi Yan Xue Ye Xue Za Zhi 21(2): 300-304, 2013

Incidence and risk factors of immune reconstitution inflammatory syndrome in HIV-TB coinfected patients. Brazilian Journal of Infectious Diseases: An Official Publication of the Brazilian Society of Infectious Diseases 15(6): 553-559, 2011

Incidence and risk factors of immune reconstitution inflammatory syndrome in HIV-TB coinfected patients. The Brazilian Journal of Infectious Diseases 15(6): 553-559, 2011

Incidence, clinical spectrum, risk factors and impact of HIV-associated immune reconstitution inflammatory syndrome in South Africa. Plos one 7(11): E40623, 2012