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Numerical estimation of -aminobutyric acid (Gaba) -containing neurons in three thalamic nuclei of the cat: Direct Gaba immunocytochemistry

Madarász, M.; Somogyi, G..; Somogyi, J.; Hámori, J.

Neuroscience Letters 61(1-2): 73-78

1985


ISSN/ISBN: 0304-3940
DOI: 10.1016/0304-3940(85)90403-3
Accession: 066908233

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The percentage of neurons that are immunoreactive for the inhibitory neurotransmitter, gamma-aminobutyric acid (GABA) was determined within: (1) the lateral geniculate nucleus (LGN), (2) the ventrobasal complex (VB) and (3) the antero-ventral nucleus (AV) of the thalamus in the cat. An antiserum to GABA was used to stain GABA-containing perikarya in 1.0 micrometer thick Araldite-embedded sections. Immunostained somata in all three nuclei were invariably smaller than the immuno-negative nerve cells. 27% of all neurons in the LGN, 33% in the VB and 25% in the AV were immunoreactive for GABA.

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