Section 68

EurekaMag Full Text Articles Chapter 67,196


Plobeck, N.; Delorme, D.; Wei, Z.-Y.; Yang, H.; Zhou, F.; Schwarz, P.; Gawell, L.; Gagnon, H.; Pelcman, B.; Schmidt, R.; Yue, S.Y.; Walpole, C.; Brown, W.; Zhou, E.; Labarre, M. 2000: New Diarylmethylpiperazines as Potent and Selective Nonpeptidic Opioid Receptor Agonists with Increased In Vitro Metabolic Stability. Journal of Medicinal Chemistry 43(21): 3878-3894
Portoghese, P.S. 1992: The role of concepts in structure-activity relationship studies of opioid ligands. Journal of Medicinal Chemistry 35(11): 1927-1937
Sasse, A.; Sadek, B.; Ligneau, X.; Elz, S.; Pertz, H.H.; Luger, P.; Ganellin, C.R.; Arrang, J.-M.; Schwartz, J.-C.; Schunack, W.; Stark, H. 2000: New Histamine H 3 -Receptor Ligands of the Proxifan Series: Imoproxifan and Other Selective Antagonists with High Oral in Vivo Potency. Journal of Medicinal Chemistry 43(17): 3335-3343
May, E.L. 1992: A half century in medicinal chemistry with major emphasis on pain-relieving drugs and their antagonists. Journal of Medicinal Chemistry 35(20): 3587-3594
Niiya, K.; Thompson, R.D.; Silvia, S.K.; Olsson, R.A. 1992: 2-(N'-aralkylidenehydrazino)adenosines: potent and selective coronary vasodilators. Journal of Medicinal Chemistry 35(24): 4562-4566
Kingsbury, W.D.; Boehm, J.C.; Jakas, D.R.; Holden, K.G.; Hecht, S.M.; Gallagher, G.; Caranfa, M.J.; McCabe, F.L.; Faucette, L.F.; Johnson, R.K.; Hertzberg, R.P. 1991: Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity. Journal of Medicinal Chemistry 34(1): 98-107
Halfpenny, P.R.; Horwell, D.C.; Hughes, J.; Humblet, C.; Hunter, J.C.; Rees, D.C.; Neuhaus, D. 1991: Highly selective .kappa. opioid analgesics. 4. Synthesis of some conformationally restricted naphthalene derivatives with high receptor affinity and selectivity. Journal of Medicinal Chemistry 34(1): 190-194
Schnur, R.C.; Gallaschun, R.J.; Singleton, D.H.; Grissom, M.; Sloan, D.E.; Goodwin, P.; McNiff, P.A.; Fliri, A.F.J.; Mangano, F.M. 1991: Quantitative structure-activity relationships of antitumor guanidinothiazolecarboxamides with survival enhancement for therapy in the 3Ll Lewis lung carcinoma model. Journal of Medicinal Chemistry 34(7): 1975-1982
Coburn, R.A.; Wierzba, M.; Suto, M.J.; Solo, A.J.; Triggle, A.M.; Triggle, D.J. 1988: 1,4-Dihydropyridine antagonist activities at the calcium channel: a quantitative structure-activity relationship approach. Journal of Medicinal Chemistry 31(11): 2103-2107
Sufrin, J.R.; Spiess, A.J.; Kramer, D.L.; Libby, P.R.; Porter, C.W. 1989: Synthesis and antiproliferative effects of novel 5'-fluorinated analogs of 5'-deoxy-5'-(methylthio)adenosine. Journal of Medicinal Chemistry 32(5): 997-1001
Shen, T.Y. 1981: Toward more selective antiarthritic therapy. Journal of Medicinal Chemistry 24(1): 1-5
Vincek, W.C.; Aldrich, C.S.; Borchardt, R.T.; Grunewald, G.L. 1981: Importance of the aromatic ring in adrenergic amines. 5. Nonaromatic analogs of phenylethanolamine as inhibitors of phenylethanolamine N-methyltransferase: role of hydrophobic and steric interactions. Journal of Medicinal Chemistry 24(1): 7-12
Walker, K.A.M.; Wallach, M.B.; Hirschfeld, D.R. 1981: 1-(Naphthylalkyl)-1H-imidazole derivatives, a new class of anticonvulsant agents. Journal of Medicinal Chemistry 24(1): 67-74
Murakami, K.; Takasuka, M.; Motokawa, K.; Yoshida, T. 1981: 1-Oxacephalosporins: enhancement of .beta.-lactam reactivity and antibacterial activity. Journal of Medicinal Chemistry 24(1): 88-93
Marcincal-Lefebvre, A.; Gesquiere, J.C.; Lemer, C.; Dupuis, B. 1981: (Phenylthio)phenylamine derivatives as potential antiinflammatory compounds. Journal of Medicinal Chemistry 24(7): 889-893
Anderson, R.A.; Oswald, C.; Zaneveld, L.J.D. 1981: Inhibition of human acrosin by monosaccharides and related compounds: structure-activity relationships. Journal of Medicinal Chemistry 24(11): 1288-1291
Johnson, R.E.; Soria, A.E.; O'Connor, J.R.; Dobson, R.A. 1981: Synthesis and antibacterial activity of 1-(arylamino)-1H-pyrroles and 4-(1H-pyrrol-1-ylimino)-2,5-cyclohexadienes. Journal of Medicinal Chemistry 24(11): 1314-1319