+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Aporphines. 11. Synthesis and dopaminergic activity of monohydroxyaporphines. Total synthesis of (+-)-11-hydroxyaporphine, (+-)-11-hydroxynoraporphine, and (+-)-11-hydroxy-N-propylnoraporphine



Aporphines. 11. Synthesis and dopaminergic activity of monohydroxyaporphines. Total synthesis of (+-)-11-hydroxyaporphine, (+-)-11-hydroxynoraporphine, and (+-)-11-hydroxy-N-propylnoraporphine



Journal of Medicinal Chemistry 17(10): 1090-1095




Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 067197030

Download citation: RISBibTeXText

DOI: 10.1021/jm00256a014


Related references

Aporphines. 11. Synthesis and dopaminergic acitivity of monohydroxyaporphines. Total synthesis of (plus, minus)-11-hydroxyaporphine, (plus and minus)-11-hydroxynoraporphine, and (plus, minus)-11-hydroxy-N-n-propylnoraporphine. Journal of Medicinal Chemistry 17(10): 1090-1095, 1974

Aporphines. 14. Dopaminergic and antinociceptive activity of aporphine derivatives. Synthesis of 10-hydroxyaporphines and 10-hydroxy-N-propylnoraporphine. Journal of Medicinal Chemistry 19(1): 25-29, 1976

Aporphines. 14 Dopaminergic and antinociceptive activity of aporphine derivatives. Synthesis of 10-hydroxyaporphines and 10-hydroxy-N-n-propylnoraporphine. Journal of Medicinal Chemistry 19(1): 25-29, 1976

Aporphines part 14 dopaminergic and anti nociceptive activity of aporphine derivatives synthesis of 10 hydroxy aporphines and 10 hydroxy n n propyl noraporphine. Journal Of Medicinal Chemistry: 25-29, 1976

Aporphines 65: chemical, microbial synthesis and characterization by gas chromatography/mass spectrometry of (R)-(-)-10-hydroxy 11-methoxy-N-n-propylnoraporphine, a potential metabolite of N-n-propylnorapomorphine. Biomedical and Environmental Mass Spectrometry 13(5): 223-229, 1986

Aporphines. 34. (-)-2,10,11-Trihydroxy-N-n-propylnoraporphine, a novel dopaminergic aporphine alkaloid with anticonvulsant activity. Journal of Medicinal Chemistry 24(7): 898-899, 1981

R(-) and S(+) stereoisomers of 11-hydroxy- and 11-methoxy-N-n-propylnoraporphine: central dopaminergic behavioral activity in the rat. Neuropharmacology 29(6): 527-536, 1990

Aporphines. 21. Dopaminergic activity of aporphine and benzylisoquinoline derivatives. Synthesis of 8-hydroxyaporphines and 1-(hydroxybenzyl)-2-n-propyl-1,2,3,4-tetrahydroisoquinolines. Journal of Medicinal Chemistry 20(2): 190-196, 1977

Aporphines, 21. (1,2) Dopaminergic activity of aporphine and benzylisoquinoline derivatives. Synthesis of 8-hydroxyaporphines and 1-(hydroxybenzyl)-2-n-propyl-1,2,3,4-tetrahydroisoquinolines. Journal of Medicinal Chemistry 20(2): 190-196, 1977

Radical cyclization to aporphines A new, efficient total synthesis of the aporphine glaucine and the 4,5-dioxoaporphine pontevedrine, and the first total synthesis of 5-oxoporphines. Tetrahedron 50(7): 2107-2114, 1994

Synthesis of 2-fluoro-11-hydroxy-N-propylnoraporphine: a potential dopamine D2 agonist. Organic Letters 7(15): 3239-3242, 2005

Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine. Journal of Medicinal Chemistry 31(7): 1392-1396, 1988

Studies on tetrahydroisoquinolines. XIX. Synthesis of (.+-.)-isothebaine,(.+-.)-1-hydroxy-2,9-dimethoxy-,(.+-.)-1-hydroxy-2,10-dimethoxy-,and (.+-.)-2,10-dimethoxy-aporphines,(.+-.)-2,6-dimethoxyhomomorphinandienone,and (.+-.)-1-hydroxy-2,10-dimethoxyhomoaporphine. Chemical & Pharmaceutical Bulletin 29(4): 1083-1087, 1981

Synthesis and dopamine receptor binding of dextro 2 hydroxy apo morphine and levo 2 hydroxy apo morphine and related aporphines. Abstracts Of Papers American Chemical Society: Edi 22, 1981

Synthesis of hydroxy aporphines and a study of their possible dopamine receptor stimulating properties. Pharmacologist 13(2): 252, 1971