Current status of endovascular therapy for acute ischemic stroke

Yamagami, H.; Sakai, N.

Rinsho Shinkeigaku 53(11): 1166-1168


ISSN/ISBN: 0009-918X
DOI: 10.5692/clinicalneurol.53.1166
Accession: 068511207

Download citation:  

Article/Abstract emailed within 0-6 h
Payments are secure & encrypted
Powered by Stripe
Powered by PayPal

Endovascular therapy (EVT) is performed in patients with acute ischemic stroke due to major artery occlusion, if they were ineligible of intravenous (IV) rt-PA or failure to achieve reperfusion by IV rt-PA. In Japan, intra-arterial thrombolysis has been generally performed, and mechanical thrombectomy using Merci retriever and Penumbra system are gradually spreading. In 2013, the results of three randomized trials (IMS 3, SYNTHESIS expansion, and MR RESCUE) were published, and they could not prove the usefulness of EVT in patients with acute ischemic stroke compared with standard therapy including IV rt-PA. However, these trials suggested important issues of EVT. Especially, adequate selection of patients, improvement of reperfusion rate, and shorter onset to reperfusion time are needed to establish the usefulness of EVT.