Prognostic Factors in Patients with Non-Metastatic Renal cell Carcinoma

Inomiya, H.; Isaka, S.; Okano, T.; Shimazaki, J.; Igarashi, T.; Matsuzaki, O.

The Japanese Journal of Urology 87(9): 1099-1104


DOI: 10.5980/jpnjurol1989.87.1099
Accession: 068514288

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The objective of this study is to evaluate prognostic factors of non-metastatic renal cell carcinoma using univariate and multivariate statistical methods. 390 patients who were performed radical surgery in our hospital between 1960 and 1994 were entered to this study. Kaplan-Meier method with log-rank test and Cox's proportional hazard model were used for statistical analysis. Chief complaints, tumor localization on kidney, tumor size, fever, hemoglobin, C-reactive protein, erythrocyte sedimentation rate, immunosuppressive acidic protein, operative method, blood loss, histologic grade, cell type, pT, pN and pV revealed to have prognostic statistical significance in the univariate analysis. Whereas, sex, age, blood type, hypertension, affected side and preoperative embolization did not. In the multivariate analysis of the preoperatively evaluable factors, CRP, tumor size and tumor localization proved to be significant prognostic predictors in this order. When the pathological factors were included to the multivariate analysis, pV, historogic grade and pN revealed to be significant prognostic predictors in this order. These results suggest that pathological factors were significant prognostic predictors for non-metastatic renal cell carcinoma.