Bioconversion and biosynthesis of 16-membered macrolide antibiotic, tylosin, using enzyme inhibitor: Cerulenin

Omura, S.; Kitao, C.; Miyazawa, J.; Imai, H.; Takeshima, H.

The Journal of Antibiotics 31(3): 254-256

1978


DOI: 10.7164/antibiotics.31.254
Accession: 068515791

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Abstract
The final steps of the biosynthetic pathway of tylosin and relomycin were studied by using the antibiotic cerulin. Streptomyces fradiae was the producing strain.