Penitricin, a new class of antibiotic produced by Penicillium aculeatum. Iv. Biosynthesis

Okuda, T.; Furumai, T.

The Journal of Antibiotics 38(5): 631-635

1985


DOI: 10.7164/antibiotics.38.631
Accession: 068516191

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Abstract
Bioconversion experiments using washed mycelia of Penicillium aculeatum NR 5165 and NR 6216 revealed that penitricin (Ro 09-0804, hydroxymethylcyclopropenone) was biosynthesized from trans-2-butene-1,4-diol via 4-hydroxycrotonaldehyde.