Guinea pig antiserum to mouse cytotoxic T lymphocytes and their precursors

Rothstein, T.L.; Mage, M.G.; Mond, J.; McHugh, L.L.

Journal of Immunology 120(1): 209-215


ISSN/ISBN: 0022-1767
PMID: 24072
Accession: 068518312

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An antiserum specific for cytotoxic T positive spleen cells. Antibody activity was independent of the H-2 or Ly allotypes of the cells being treated. Helper activity and proliferative responses to concanavalin A and to phytohemagglutinin were unaffected. There was a variable effect on the mixed lymphocyte reaction, and partial inhibition of graft vs. host activity.