New inhibitors of histamine-N-methyltransferase

Beaven, M.A.; Shaff, R.E.

Biochemical Pharmacology 28(2): 183-188

1979


ISSN/ISBN: 0006-2952
PMID: 34400
DOI: 10.1016/0006-2952(79)90500-8
Accession: 068518599

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Abstract
A variety of histamine agonists, antagonists and their analogs were tested for their ability to inhibit guinea-pig brain and rat kidney histamine-N-methyltransferase , which has no histamine agonist activity. SKF 91488, therefore, may be especially useful in histamine metabolism studies.