Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: I. Viral shedding, immunologic response, and associated illness

Richardson, L.S.; Belshe, R.B.; London, W.T.; Sly, D.L.; Prevar, D.A.; Camargo, E.; Chanock, R.M.

Journal of Medical Virology 3(2): 91-100

1978


ISSN/ISBN: 0146-6615
PMID: 104004
DOI: 10.1002/jmv.1890030202
Accession: 068520783

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Abstract
Approximately 104 plaque-forming units (pfu) of five temperature-sensitive (ts) mutants of respiratory syncytial (RS) virus were administered intranasally to seronegative chimpanzees to evaluate their level of attenuation.