The pharmaco-kinetics of angiographic contrast media, with special reference to the extra-vascular space. An experimental study on dogs. Paper II. Pharmaco-kinetics of an angiographic contrast medium used for selective angiography

Lagemann, K.

Rofo Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 123(6): 515-521


ISSN/ISBN: 1438-9029
PMID: 129404
DOI: 10.1055/s-0029-1230247
Accession: 068521357

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Basic studies were carried out on experimental animals in order to investigate the pharmaco-kinetics of angiographic contrast media when used in various ways. Injections were carried out through angiographic catheters in a "physiological angiographic" manner. Measurements obtained by using radioactive compounds have shown that the distribution and excretion of the contrast medium are independent of the site of injection. The kinetics of the contrast within an organ do not differ, whether it is injected selectively or not. The results of all the experiments will be discussed at the conclusion of the third paper.