Dehydroepiandrosterone concentration in adipose tissue of normal and overweight subjects

Fehér, T.; Halmy, L.; Bodrogi, L.; Kazik, M.H.

Hormone and Metabolic Research 8(5): 372-374


ISSN/ISBN: 0018-5043
PMID: 135717
DOI: 10.1055/s-0028-1093616
Accession: 068521649

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Unconjugated dehydroepiandrosterone has been isolated from human abdominal adipose tissue and identified by double isotope derivatization and recrystallization to constant isotope ratio. Gas chromatography with electron capture detection revealed an actual dehydroepiandrosterone concentration between 0.32 to 2.82 mug/g in adipose tissue of normal and overweight subjects. The approximate dehydroepiandrosterone content of the total adipose tissue mass varied between 30 and 173 mg in subjects with severe obesity.