Persistence of latex-agglutination inhibiting and neutralizing antibodies against enterovirus in the healthy population

Schmidt, W.A.; Brade, H.; Klein, M.; Krämer, U.

Deutsche Medizinische Wochenschrift 100(33): 1663-1666


ISSN/ISBN: 0012-0472
PMID: 169112
DOI: 10.1055/s-0028-1106440
Accession: 068523012

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Sera of 122 persons were examined by the neutralization and latex-agglutination inhibition tests for antibodies against Polio type I, Coxsackie virus type A 9 and B 4, as well as Echo virus type 9. With increasing age there was a titre difference between latex-agglutination inhibiting and neutralizing antibodies, due to the earlier fall in the former. These antibodies, contrary to neutralizing ones, were in the lower titre region. The results confirmed the usefulness of the latex-agglutination inhibition test in the diagnosis of acute enterovirus infections.