A possible role of calcium in the action of glucagon, cAMP and dibutyryl cAMP on the metabolism of free fatty acids by rat hepatocytes

Soler-Argilaga, C.; Russell, R.L.; Werner, H.V.; Heimberg, M.

Biochemical and Biophysical Research Communications 85(1): 249-256


ISSN/ISBN: 0006-291X
PMID: 217373
DOI: 10.1016/s0006-291x(78)80036-9
Accession: 068524430

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The effects of Ca2+ on the actions of glucagon c oleate was impaired when the hepatocytes were depleted of Ca. Ca plays an important role in hepatic triacylglycerol synthesis and in ketogenesis and on the actions of glucagon and adenylic cyclic nucleotides on these metabolic pathways.