Effects of cordycepin and bromodeoxyuridine on the embryonic development of the earthworm Eisenia foetida (Bicolor)

Devriès, J.

Archives de Biologie 90(4): 381-396

1979


ISSN/ISBN: 0003-9624
PMID: 317939
Accession: 068526169

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Abstract
The effects of cordycepin and bromodeoxyuridine on embryonic development of the earthworm E. faetida were studied by continuous and short treatments applied to different pregastrula stages. These inhibitors cause arrests and anomalies of embryogenesis. A clear decrease in sensitivity is observed after the fundamental 7-cell stage. This result represents an argument for the hypothesis according to which the 1st ecto-mesodermic embryonic determination occurring at this stage (2d, 2D) corresponds to a precise genetic program; this probably relates to the mitotic rhythm of the D quadrant.